DescriptionINTRODUCTION: Several studies report that the adhesive system used may affect the color stability of the restoration, however there are conflicting opinions OBJECTIVES: Evaluate the influence of different adhesive systems on the colorimetric alteration of bulk fill resins. MATERIAL AND METHODS: 120 composite discs made with UD3 (Micerim, Italy) were divided into 4 groups, one control, without adhesive, and 3 study groups in which were applied the adhesive: Clearfil SE Bond 2 (Kuraray, Japan), Futurabond NR (VOCO, Germany) and OptiBond XTR (Kerr, EUA). Then 240 discs of each resin: Fill-Up (Colténe, Switzerland) and Xtra-Fill (VOCO, Germany) were prepared on the initial discs. A colorimetric evaluation was performed initially, 15 and 30 days using a spectrophotometer (VITA Easyshade® Compact, Vita Zahnfabrik, Bad Säckingen, Germany). During that period the discs were in a dye solution. Data analysis was performed using the statistical analysis program SPSS® v.25.0 (Statistical Package for the Social Sciences, IBM, USA). RESULTS AND DISCUSSION: Through the study, it was found that the adhesive system used altered the color of the final restoration because there were significant differences between the groups. The adhesive with lower global color variation was Clearfil SE Bond 2, however, the one with the lowest variation of results was the Futurabond NR. It has been found that the Xtra-Fill is less susceptible to color changes since it had less global color variation. CONCLUSION: When using translucent resins such bulk fill resins, it is necessary to take into consideration the adhesive system used, always seeking to increase the aesthetic longevity of the restoration.