In the face of the COVID-19 pandemic, it was observed that SARS-CoV-2 infection can progress to severe respiratory disease, even leading to death. Among the various complications of COVID-19, the occurrence of thromboembolic events is observed. Parallel to this, there is a close relationship between cancer and venous thromboembolism, with an increased risk of people with cancer developing a thromboembolic event when compared to the general population. In this way, the following research questions arose: are people with cancer and diagnosed with COVID-19 at greater risk for developing thromboembolic events? And: how can nursing contribute to preventing thromboembolic events in people with cancer and COVID-19? The overall objective of this research was to analyze the association between COVID-19 infection and thromboembolic events in people with cancer during the first year of the pandemic. The present study intends to contribute to the assistance to people with cancer and COVID-19, guiding the practice and suggesting conducts aimed at preventing thromboembolic events. In this way, research tends to strengthen the teaching of oncology nursing and scientific research, through the publication of studies, which adds new knowledge and values the work of nurses. The research has great social relevance, because, in the context of thromboembolic events, cardiovascular diseases are the ones that most affect the world population, accounting for a high number of deaths. In addition, considering the Ministry of Health's agenda of research priorities, it is observed that this research tends to contribute to the assessment of thromboembolic events as adverse events in the health care of people with cancer. Therefore, we opted for a case-control study, carried out at the units of the José Alencar Gomes da Silva National Cancer Institute, in the city of Rio de Janeiro, Brazil. Medical records of people with cancer, assisted in the first year of the COVID-19 pandemic, were selected. The research addressed two groups, subdivided into two groups each, totaling four groups: a group of people with thromboembolic events was subdivided into a group with COVID-19 and another without COVID-19 and another group with people without thromboembolic events, also subdivided into one group with COVID-19 and one without COVID-19. After analyzing the results, a search in the literature was carried out in order to identify data that, associated with the main findings, would support a nursing strategy in the prevention of these events. The study was approved by the Research Ethics Committees of the institutions involved, according to opinions nº: 4,486,636 and 4,509,083. 828 participants were included, of which 11.59% had a diagnosis of COVID-19. The case group had 388 records and the control group 440. Overall, the population was mostly female, white, with a mean age of 58.2 years. The most prevalent comorbidity was hypertension, followed by diabetes. Of the total, 90.5% had malignant neoplasia, 73.91% had active cancer and the most frequent tumor site… Advisors/Committee Members: Fuly, Patrícia dos Santos Claro (advisor1), http://lattes.cnpq.br/7625867664431524 (advisor1Lattes), Alves, Paulo Jorge Pereira (advisor-co1), http://lattes.cnpq.br/3456052972991332 (advisor-co1Lattes), Chagas, Marléa Crescêncio (referee1), http://lattes.cnpq.br/6090071913050951 (referee1Lattes), Santos, Mauro Leonardo Salvador Caldeira dos (referee2), http://lattes.cnpq.br/8526777752396550 (referee2Lattes), Andrade, Karla Biancha Silva de (referee3), http://lattes.cnpq.br/8981588528468134 (referee3Lattes), Camacho, Alessandra Conceição Leite Funchal (referee4), http://lattes.cnpq.br/8877729715215331 (referee4Lattes), http://lattes.cnpq.br/5866336645264235 (authorLattes).
| Period | 2 Sept 2023 |
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| Held at | Universidade Federal Fluminense, Brazil |
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| Degree of Recognition | PhD |
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