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20152024

Research activity per year

Personal profile

Biography

I am a biomedical doctor from the Federal University of Rio Grande do Norte, with qualifications in clinical analysis, haematology, and hemotherapy. I also have a Master's degree in Medical Parasitology and a PhD in Biomedical Sciences within the speciality of Cellular and Molecular Biology, both awarded by the Institute of Hygiene and Tropical Medicine of the New University of Lisbon (IHMT NOVA). During my degree, master and doctorate, and later on as a project fellow I did studies of antimalarial drugs using developed and implemented in vitro mammalian cell line cultures, cytotoxicity and genotoxicity assays, stage-specific activity, mitochondrial membrane potential, and gametocytocidal activity, as well as in vivo antiplasmodial activity assays using murine models and transmission-blocking activity. In my post-doc on a European project on Chagas Disease, funded by the European Union´s Horizon 2020 at IHMT NOVA, I studied to bridge the gap between the preclinical and clinical development of a needle-free vaccine against Trypanosoma cruzi, by performing preclinical and clinical phase 1 studies of a vaccine with proven efficacy in preclinical models. In this project, I had the opportunity to expand my experience in immunological methodologies, of which I highlight cell cultures, multiparametric flow cytometry, PCR, RT-qPCR and cloning and transfection of bacteria. During this time, I had the opportunity to join the teams of two FCT-funded projects (PTDC/BTM-SAL/29786/2017 and PTDC/CVT-CVT/0228/2020), and one (EXPL/CVT-CVT/0175/2021) as principal investigator. In the last months, I worked as a collaborating junior researcher at NOVA School of Science and Technology (FCT NOVA) in the Glycoimmunology lab, which aims to elucidate the role of Glycosylation in immune response and cancer progression and in developing novel cell and antibody-based immunotherapy. I also had the opportunity to give scientific and technical support to other researchers as well as student supervision and lab management. At this moment, I am working on a project funded by the La Caixa Foundation, that aims to dissect how a protein acts as a crucial regulator of ageing and age-related diseases in the Vascular Biology and Disease Lab at at Catolica Biomedical Research Centre (CBR).

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD, Study of antimalarial activity of new endoperoxides: potential parasite targets and mechanisms of action, NOVA University Lisbon

20 Jan 201426 Jun 2019

Award Date: 26 Jun 2019

Master, Avaliação in vitro e in vivo da atividade antimalárica dos trioxolanos NAC89, LDC67 e LC50 em estirpes sensíveis e resistentes à artemisinina e ao artesunato, NOVA University Lisbon

15 Oct 201014 Dec 2012

Award Date: 14 Dec 2012

Bachelor

Aug 2005Feb 2010

Award Date: 1 Feb 2010

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