Projects per year
Personal profile
Biography
Manuela Machado is, nowadays, a Researcher at Centro de Biotecnologia e Química Fina (CBQF), a member of its Safety Committee, and the Researcher responsible for the Project Vertical Alimentar of the PRR-funded Pacto da Bioeconomia Azul project. In it, she manages the day-to-day interactions with industrial and academic partners and the overall technical and financial execution of the project. Throughout her research career, she has been involved in the development of agro-food-based solutions for the food and nutraceutical industries. This strong industrial focus is reflected in the participation in 4 industrial R&D projects and an additional 1 of a more fundamental nature. Additionally, this relation led to the creation of a functional canned tuna with EFSA-approved cardiovascular health-related allegations which is currently in commercialization. Analysis of her CV shows that her research efforts followed three main topics: i) Valorisation of agro-food byproducts in a circular economy context through the exploitation of their biological potential; ii) characterization of extracted compounds biological potential targeting desirable properties such as cellular metabolism and immune response modulation; iii) designing of delivery and formulation solutions for the usage and delivery of bioactive compounds. Author of 28 international peer-reviewed papers and 6 book chapters, of which she is the first author in 50% of them (14 papers and 3 book chapters). Additionally, she has also been Invited Editor in the Bioactive Lipids book published by Elsevier. According to Scopus (December 2023) she has been cited 189 times by 172 papers which resulted in an h-index of 6. Her main publication areas have been Agricultural and Biological Sciences followed by Biochemistry, Genetics, and Molecular Biology. She participated in 12 national and international conferences presenting 3 oral and 13 poster communications. She has tutored 4 visiting MSc students and various BSc students. Due to the high quality of her scientific work during her PhD research, she has been awarded the First Prize in the Mentorado Comendador Arménio Miranda by Frulact Academy.
Education/Academic qualification
PhD, Functional lipid enriched dairy products geared towards obesity management: technological feasibility and nutraceutical potential, Universidade Católica Portuguesa
1 Jan 2019 → 19 Apr 2023
Award Date: 19 Apr 2023
Master
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Collaborations and top research areas from the last five years
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HERMETIA: Sustainable and circular organic waste management through BSF
Pintado, M. M. (PI) & Machado, M. (Researcher)
2/01/26 → 31/12/28
Project: Innovation
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FERDINAND: Fish-dERiveD Innovative ageNts As Novel therapeutics for carDiometabolic diseases
Machado, M. (PI), Gomes, A. M. (Researcher), Correia, M. (Researcher), Costa, E. (Researcher) & Sousa, S. (Researcher)
Fundação para a Ciência e a Tecnologia
2/10/25 → 31/08/28
Project: Research
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WiSe: Aged wine sediments as a dietary supplement for inflammatory bowel disease modulation
Silva, S. (PI), Machado, M. (Researcher), Ferreira, A. S. (Researcher), Castro, L. M. G. (Researcher) & Magalhães, R. (Researcher)
Fundação para a Ciência e a Tecnologia
2/10/25 → 31/08/28
Project: Research
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SINFONIA: Sustainable Agroecosystems, Food Innovation, and Artistic Practices for Climate Adaptation
Pinto, E. (PI), Bexiga, M. G. (CoPI), Costa, P. R. (CoPI), Morais, A. M. M. B. (Researcher), Gomes, A. M. (Researcher), Martins, A. P. (Researcher), Rangel, A. O. S. S. (Researcher), Santos, C. S. D. (Researcher), Manaia, C. (Researcher), Kekhasharú Tavaria, F. (Researcher), Vaz-Moreira, I. (Researcher), Barbosa, J. C. (Researcher), Botelho, J. (Researcher), Machado, M. (Researcher), Barbosa, M. I. (Researcher), Pintado, M. M. (Researcher), Correia, M. (Researcher), Silva, M. N. D. (Researcher), Vasconcelos, M. (Researcher), Teixeira, P. (Researcher), Castro, P. M. L. (Researcher), Rodrigues, P. M. (Researcher), Duarte, R. (Researcher), Mesquita, R. (Researcher), Magalhães, R. (Researcher), Sousa, S. (Researcher), Pereira, S. (Researcher), Ribas, T. (Researcher), Brandão, T. R. S. (Researcher), Alves, P. (Researcher), Almeida, A. (Researcher), Costa, T. (Researcher), Baltazar, A. (Researcher), Sá, C. (Researcher), Ribas, D. (Researcher), Castro, L. (Researcher), Revez, M. J. (Researcher), Carvalho, J. V. (Researcher), Natálio, C. (Researcher), Bordalo, R. (Researcher) & Leitão, A. (Researcher)
1/07/25 → 30/06/28
Project: Innovation
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gBiOT: Nutraceutical biopolymeric-biocatalytic microbot against gut inflammatory disorders
Coscueta, E. (PI), Pintado, M. M. (CoPI), Machado, M. (Researcher), Coelho, M. (Researcher), Rodrigues, P. M. (Researcher), Sousa, A. S. D. S. (Researcher), Sousa, C. (Researcher), Magalhães, A. (Researcher) & Santos Matos, R. D. (Researcher)
Fundação para a Ciência e a Tecnologia
1/03/23 → 28/02/27
Project: Research
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Understanding the anti-obesity potential of an avocado oil-rich cheese through an in vitro co-culture intestine cell model
Machado, M., Costa, E. M., Silva, S., Rodriguez-Alcalá, L. M., Gomes, A. M. & Pintado, M., 7 Aug 2023, In: Molecules. 28, 15, 12 p., 5923.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)57 Downloads -
Bigels as delivery systems of bioactive fatty acids present in functional edible oils: coconut, avocado, and pomegranate
Machado, M., Sousa, S. C., Rodríguez-Alcalá, L. M., Pintado, M. & Gomes, A. M., 21 Apr 2023, In: Gels. 9, 4, 12 p., 349.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)95 Downloads -
Anti-obesity potential of a yogurt functionalized with a CLNA-rich pomegranate oil
Machado, M., Sousa, S., Rodriguez-Alcalá, L. M., Gomes, A. M. & Pintado, M., Nov 2023, In: Food research international. 173, 12 p., 113364.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)82 Downloads -
Pomegranate oil’s potential as an anti-obesity ingredient
Machado, M., Costa, E. M., Silva, S., Rodriguez-Alcalá, L. M., Gomes, A. M. & Pintado, M., 4 Aug 2022, In: Molecules. 27, 15, 14 p., 4958.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)123 Downloads -
Are antimicrobial peptides a 21st-century solution for atopic dermatitis?
Machado, M., Silva, S. & Costa, E. M., Sept 2023, In: International Journal of Molecular Sciences. 24, 17, 18 p., 13460.Research output: Contribution to journal › Review article › peer-review
Open AccessFile11 Citations (Scopus)54 Downloads
Datasets
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MassIVE MSV000100133: effect of processing and mcrobial inoculation on the peptidomics of goat cheeses
Moraes, A. E. A. D. (Contributor), Alves, A. M. D. S. (Contributor), Rossini, B. C. (Contributor), Costa, C. N. M. (Contributor), Coscueta, E. R. (Contributor), Galland, F. A. B. (Contributor), Oliveira, J. M. C. D. (Contributor), Santos, L. D. D. (Contributor), Machado, M. (Contributor), Oliveira, M. E. G. D. (Contributor), Pintado, M. E. (Contributor) & Pacheco, M. T. B. (Contributor), MassIVE, 6 Dec 2025
DOI: 10.25345/C5B56DJ2Q
Research data
Prizes
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Best Poster Award 7th International Conference WASTES: Solutions, Treatments and Oopportunities
Machado, M. (Recipient), Costa, E. (Recipient), Cação, A. (Recipient), Augusto, H. (Recipient) & Pintado, M. M. (Recipient), 5 Sept 2025
Prize
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CBQF Annual Incentive for Extraordinary Outputs during 2023
Machado, M. (Recipient), 2024
Prize: Other distinction
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Conserva Azul – 2nd place at Expo Fish Portugal
Machado, M. (Recipient), Tato, I. (Recipient) & Pintado, M. M. (Recipient), 2024
Prize
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Desenvolvimento de um iogurte com lípidos bioativos para prevenção da obesidade
Machado, M. (Recipient), Gomes, A. M. (Recipient) & Pintado, M. M. (Recipient), 2021
Prize
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Editor's Choice Award
Machado, M. (Recipient), Bautista-Hérnandez, I. (Recipient), García, R. G. (Recipient), Silva, S. (Recipient) & Costa, E. (Recipient), 13 Feb 2026
Prize: Honorary award
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Activities
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Probiotic modulation of adipogenesis: screening Lactobacillus and Bifidobacterium strains for anti-adipogenic activity
Machado, M. (Supervisor), Silva, S. (Co-supervisor), Costa, E. (Co-supervisor), Oliveira, M. (Student) & Sequeira, I. (Student)
Jan 2026 → Jun 2026Activity: Supervision
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Gels (Journal)
Costa, E. (Guest editor), Machado, M. (Guest editor) & Silva, S. (Guest editor)
24 Feb 2026 → 30 Nov 2026Activity: Publication peer-review and editorial work › Editorial work
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Antimicrobial peptide production by adipocytes in response to bacterial stimulation
Machado, M. (Supervisor), Silva, S. (Co-supervisor), Costa, E. (Co-supervisor) & Oliveira Lago, I. (Student)
Jan 2026 → Jun 2026Activity: Supervision
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Wine byproduct extracts as modulators of Lactobacillus and intestinal cells
Silva, S. (Supervisor), Machado, M. (Co-supervisor), Costa, E. (Co-supervisor), Borges, G. (Student) & Aguiar, J. (Student)
Jan 2026 → Jun 2026Activity: Supervision
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Inhibition of quorum sensing in pathogenic bacteria using natural molecules as a non-antibiotic antivirulence strategy
Silva, S. (Co-supervisor), Machado, M. (Co-supervisor), Costa, E. (Supervisor) & Magalhães, M. (Student)
Jan 2026 → Jun 2026Activity: Supervision
Thesis
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Functional lipid enriched dairy products geared towards obesity management: technological feasibility and nutraceutical potential
Machado, M. D. F. F. (Student), Pintado, M. M. E. (Supervisor), Gomes, A. M. P. (Co-Supervisor) & Alcalá, L. M. R. (Co-Supervisor), 19 Apr 2023Student thesis: Doctoral Thesis