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Marta Alenquer

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Marta Alenquer

 https://orcid.org/0000-0003-3062-1222
    20062026

    Research activity per year

    Personal profile

    Biography

    Marta Alenquer is a virologist with longstanding expertise in herpesviruses, influenza A virus and, more recently, in SARS-CoV-2. Her scientific career has been dedicated to understanding virus-host interactions at both the cellular and organismal levels, identifying host factors and pathways essential for viral replication, as well as viral proteins and virulence factors that impact viral disease in animal models of infection. Her achievements in the field include: 1) the paradigm-changing discovery that influenza A virus creates biomolecular condensates with liquid properties dedicated to the assembly of the viral genome (Alenquer et al., 2019, Nat. comms, 10:1629; Etibor et al., 2023, eLife.85182); 2) the development of an alternative method to diagnose SARS-CoV-2 infection in children using saliva and bypassing RNA extraction (Alenquer et al., 2022, Plos one 17 (6), e0268388); 3)  the development of a pseudovirus-based neutralization assay to study the ability of evolving SARS-CoV-2 variants to escape pre-existing immunity developed upon natural infection or vaccination (Alenquer et al., 2021, PLoS pathogens 17 (8), e1009772).

    Keywords

    • QR355 Virology
    • Influenza A Virus
    • SARS-CoV-2
    • Viral pathogenesis
    • Cell Biology of viral infection
    • Molecular biology
    • Immunology

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

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    Collaborations and top research areas from the last five years

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    • Age-dependent disease tolerance to SARS-CoV-2 infection

      Rastogi, S. T., Mesquita, M., Fonseca, D. M., Salazar, S., Cardoso, S., Faisca, P., Drotleff, B., Alenquer, M., Lone, J.-C., Miguel, V., Sancho, D., Herrero, L., Paixão, T., Amorim, M. J., Jentho, E., Graça, L., Kitoko, J. Z. & Soares, M. P., 30 Jun 2026, bioRxiv, 80 p.

      Research output: Working paper › Preprint

      Open Access
      File
      16 Downloads

    • Insights into the mechanism of action of the bipartite fusion module of SARS-CoV-2 spike protein

      Buga, C. C., Valerio, M., Alenquer, M., Miranda, M. P. D., Melo, M. N., Castanho, M. A. R. B., Amorim, M. J., Soares, C. M., Vicente, J. B., Veiga, A. S. & Lousa, D., 15 Sept 2026, (Accepted/In press) In: Journal of Virology. 27 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      File
      5 Downloads

    • A metabolite-based resistance mechanism against malaria

      Figueiredo, A. M., Rastogi, S. T., Ramos, S., Nogueira, F., Villiers, K. D., Sousa, A. G. G. D., Votborg-Novel, L., Wedel, C. V., Tober-Lau, P., Jentho, E., Pagnotta, S., Mesquita, M., Cardoso, S., Bortolussi, G., Muro, A. F., Tranfield, E. M., Thibaud, J., Duarte, D., Sousa, A. L. & Pinto, S. N. & 17 others, Kitoko, J., Mombo-Ngoma, G., Mischlinger, J., Junttila, S., Alenquer, M., Amorim, M. J., Vasavda, C., Bosma, P. J., Violante, S., Drotleff, B., Paixão, T., Portugal, S., Kurth, F., Elo, L. L., Paul, B. D., Martins, R. & Soares, M. P., 26 Feb 2025, bioRxiv, 23 p.

      Research output: Working paper › Preprint

      Open Access
      File
      7 Downloads

    • A metabolite-based resistance mechanism against malaria

      Figueiredo, A., Rastogi, S. T., Ramos, S., Nogueira, F., Villiers, K. D., Sousa, A. G. G. D., Votborg-Novel, L., Wedel, C. V., Tober-Lau, P., Jentho, E., Pagnotta, S., Mesquita, M., Cardoso, S., Bortolussi, G., Muro, A. F., Tranfield, E. M., Thibaud, J., Duarte, D., Sousa, A. L. & Pinto, S. N. & 17 others, Kitoko, J., Mombo-Ngoma, G., Mischlinger, J., Junttila, S., Alenquer, M., Amorim, M. J., Vasavda, C., Bosma, P. J., Violante, S., Drotleff, B., Paixâo, T., Portugal, S., Kurth, F., Elo, L. L., Paul, B. D., Martins, R. & Soares, M. P., 12 Jun 2025, In: Science. 388, 6752, 17 p., eadq6741.

      Research output: Contribution to journal › Article › peer-review

      10 Citations (Scopus)

    • Combining biophysibs and AI to develop next-generation antiviral Biopharmaceuticals

      Silva, D. H., Moreira, P., Conceição, C. J. F., Buga, C. C., Parada, M., Teixeira, R., Silva, B. V., Miranda, M., Cruz-Oliveira, C., Melo, M. N., Abreu, I. A., Valpuesta, J. M., Alenquer, M., Amorim, M. J., Veiga, A. S., Castnaho, M. A. R. B., Soares, C. M., Vicente, J. B. & Lousa, D., 2 Jun 2025, In: European Biophysics Journal. 54, Suppl. 1, p. S101-S102 2 p., P-1.8.

      Research output: Contribution to journal › Meeting abstract › peer-review

    View all 34 research outputs
    • 1 Organising a conference, workshop, ...