Projects per year
Personal profile
Biography
I am the head of the Chromosome Dynamics lab and vice-director at Católica Biomedical Research Centre (CBR), and an Associate Professor at Católica Medical School. My undergraduate studies were in Biochemistry at the Faculdade de Ciências of the Universidade do Porto. My PhD, integrated into the Doctoral Programme in Experimental Biology and Biomedicine of CNC (Uni. Coimbra), was performed at Instituto de Biologia Molecular e Celular (IBMC), University of Porto, under the supervision of Prof. Claudio Sunkel and completed in 2007. My postdoctoral work was conducted at the Department of Biochemistry, University of Oxford, UK, under the supervision of Prof. Kim Nasmyth. In 2012 I started my independent research group, the Chromosome Dynamics lab, at the Instituto Gulbenkian de Ciência (IGC) in Oeiras, Portugal. Research in my laboratory aims to understand how mitotic chromosomes are assembled, how their structure impacts several processes involving the DNA molecule (e.g. transcription), and, ultimately, how failures in these processes impact mitotic fidelity, organism development and human disease. Our work has been funded by competitive grants and awards (~4MEUR), including an ERC Starting Grant, an ERC Consolidator Grant, an EMBO Installation Grant and a Marie Curie Career Integration Grant. I was elected an EMBO member in 2022.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Q Science (General)
- Cell biology
- Chromosomes
- Mitosis
- Cell cycle
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Collaborations and top research areas from the last five years
Projects
- 2 Active
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SUB-SCRIPT: Sub-chromosomal regulation of mitotic transcription inhibition
Oliveira, R. A. (PI) & Tovini, L. (Researcher)
1/09/24 → 31/08/26
Project: Research
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TopoChromo: Novel mitotic DNA topology regulators
Oliveira, R. A. (PI)
Fundação para a Ciência e a Tecnologia
1/01/23 → 31/12/25
Project: Research
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A dual-function SNF2 protein drives chromatid resolution and nascent transcripts removal in mitosis
Carmo, C., Coelho, J., Silva, R. D., Tavares, A., Boavida, A., Gaetani, P., Guilgur, L. G., Martinho, R. G. & Oliveira, R. A., 6 Sept 2023, In: EMBO Reports. 24, 9, 20 p., e56463.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Downloads -
Compromised mitotic fidelity in human pluripotent stem cells
Milagre, I., Pereira, C. & Oliveira, R. A., 25 Jul 2023, In: International Journal of Molecular Sciences. 24, 15, 13 p., 11933.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Citations (Scopus)28 Downloads -
Endoplasmic reticulum membranes are continuously required to maintain mitotic spindle size and forces
Araújo, M., Tavares, A., Vieira, D. V., Telley, I. A. & Oliveira, R. A., 1 Jan 2023, In: Life Science Alliance. 6, 1, 15 p., e202201540.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)70 Downloads -
Erratum: Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells (Genes & Development (2021) 35 (1020–1034) DOI: 10.1101/gad.348174.120)
Soares, M. A. F., Soares, D. S., Teixeira, V., Heskol, A., Bressan, R. B., Pollard, S. M., Oliveira, R. A. & Castro, D. S., 1 May 2023, In: Genes & development. 37, 9-10, p. 449-449 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas
Bowman, J. D., Silva, N., Schüftan, E., Almeida, J. M., Brattig-Correia, R., Oliveira, R. A., Tüttelmann, F., Enard, D., Navarro-Costa, P. & Lynch, V. J., 30 Oct 2023, bioRxiv, 65 p.Research output: Working paper › Preprint
Open AccessFile6 Downloads