Personal profile
Biography
I am the head of the Chromosome Dynamics lab and vice-director at Católica Biomedical Research Centre (CBR), and an Associate Professor at Católica Medical School. My undergraduate studies were in Biochemistry at the Faculdade de Ciências of the Universidade do Porto. My PhD, integrated into the Doctoral Programme in Experimental Biology and Biomedicine of CNC (Uni. Coimbra), was performed at Instituto de Biologia Molecular e Celular (IBMC), University of Porto, under the supervision of Prof. Claudio Sunkel and completed in 2007. My postdoctoral work was conducted at the Department of Biochemistry, University of Oxford, UK, under the supervision of Prof. Kim Nasmyth. In 2012 I started my independent research group, the Chromosome Dynamics lab, at the Instituto Gulbenkian de Ciência (IGC) in Oeiras, Portugal. Research in my laboratory aims to understand how mitotic chromosomes are assembled, how their structure impacts several processes involving the DNA molecule (e.g. transcription), and, ultimately, how failures in these processes impact mitotic fidelity, organism development and human disease. Our work has been funded by competitive grants and awards (~4MEUR), including an ERC Starting Grant, an ERC Consolidator Grant, an EMBO Installation Grant and a Marie Curie Career Integration Grant. I was elected an EMBO member in 2022.
Keywords
- Q Science (General)
- Cell biology
- Chromosomes
- Mitosis
- Cell cycle
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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SpermChromo: Chromosome architecture in spermatogenesis – from bench to bedside
Oliveira, R. A. (PI)
22/12/25 → 20/12/28
Project: Research
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SUB-SCRIPT: Sub-chromosomal regulation of mitotic transcription inhibition
Oliveira, R. A. (PI) & Tovini, L. (Researcher)
1/09/24 → 31/08/26
Project: Research
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CohesiNet: Cohesin and its regulators: from chromosome dynamics and nuclear architecture to human diseases
Oliveira, R. A. (PI)
1/01/23 → 31/12/27
Project: Research
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ChromoSilence: Chromosome-based mechanisms of transcriptional inactivation during mitosis
Oliveira, R. A. (PI)
1/10/21 → 30/09/26
Project: Research
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TopoChromo: Novel mitotic DNA topology regulators
Oliveira, R. A. (PI)
Fundação para a Ciência e a Tecnologia
1/01/23 → 31/12/25
Project: Research
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Removal of nascent transcripts by TTF2 is required for efficient sister chromatid resolution in human cells
Tovini, L., Milagre, I., Peneda, C. & Oliveira, R. A., 27 Jan 2026, bioRxiv, 23 p.Research output: Working paper › Preprint
Open AccessFile5 Downloads -
Common mechanistic pathways in rare congenital syndromes with primary microcephaly
Jorge, X., Milagre, I., Ferreira, A., Calado, S., Oliveira, R. & Carvalhal, S., 24 Jan 2025, In: Medicine (United States). 104, 4, p. 8-9 2 p., P4.Research output: Contribution to journal › Meeting Abstract › peer-review
Open AccessFile41 Downloads -
Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas
Bowman, J. D., Silva, N., Schüftan, E., Almeida, J. M., Brattig-Correia, R., Oliveira, R. A., Tüttelmann, F., Enard, D., Navarro-Costa, P. & Lynch, V., 9 May 2024, eLife Sciences Publications, 47 p.Research output: Working paper › Preprint
Open AccessFile11 Downloads -
A dual-function SNF2 protein drives chromatid resolution and nascent transcripts removal in mitosis
Carmo, C., Coelho, J., Silva, R. D., Tavares, A., Boavida, A., Gaetani, P., Guilgur, L. G., Martinho, R. G. & Oliveira, R. A., 6 Sept 2023, In: EMBO Reports. 24, 9, 20 p., e56463.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)60 Downloads -
Compromised mitotic fidelity in human pluripotent stem cells
Milagre, I., Pereira, C. & Oliveira, R. A., 25 Jul 2023, In: International Journal of Molecular Sciences. 24, 15, 13 p., 11933.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Citations (Scopus)58 Downloads