Projects per year
Personal profile
Biography
I graduated in biomedical sciences with a minor in biochemistry. I extended my undergraduate studies for one year to gain research experience in the field of tropical parasites, namely Leishmania spp. and Trypanosoma cruzi. After graduation, I pursued a PhD in veterinary parasitology, where I specialized in antigenic diversity of African trypanosomes. My work compiled computational, evolutionary and molecular biology, using both experimental models and natural infections. In my postdoc, I explored the infection biology of African trypanosomes and described the basis of acute cerebral trypanosomiasis, a violent and rare form of an otherwise chronic, wasting disease.
As I moved into research independence, I acquired competences in tissue bioengineering. My lab explores how African trypanosomes interact with their mammalian hosts via the cells that line the blood vessels. We are a versatile team, combining computational, evolutionary and infection biology techniques with tissue bioengineering systems that allow us to better reproduce disease settings. The overarching aim of the lab is to understand how trypanosome parasites survive in their mammalian hosts to prime the design of future therapies.
I have secured competitive funding from various prestigious institutions, including La Caixa Foundation, European Commission, EMBO and Fundação BIAL. My strong professional network is highighted by current and former international collaborations in the United Kingdom, Spain, Brazil, Kenya, and South Africa.
It is also highlighted by more than 15 communications in international conferences such as Molecular Parasitology Meeting, Kinetoplastid Molecular and Cell Biology Meeting, Spring Meeting of British Society of Parasitology, Annual Meeting of Sociedade Brasileira de Protozoologia, and EMBL meetings. I have been invited to present at several prestigious institutions and specialised meetings, including the Symposium on African Livestock Trypanosomiasis (Tanzania); the Institute of Biodiversity, Animal Health and Comparative Medicine of the University of Glasgow (UK); the Chronic Diseases Research Center (Portugal), the Earlham Institute (UK), and the Life and Health Sciences Research Institute (Portugal).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Veterinary Parasitology, University of Liverpool
Award Date: 4 Jun 2018
Bachelor, Biomedical Sciences w/ extramural (Biochemistry), King's College London
Award Date: 1 Jul 2014
External positions
Postdoctoral Researcher
1 Oct 2018 → 31 Aug 2023
Keywords
- QR180 Immunology
- Parasitology
- Microbiology
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Collaborations and top research areas from the last five years
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3DTrypSeq: High-resolution, high-throughput systems for decoding parasite sequestration
Pereira, S. S. (PI)
1/09/23 → 31/08/26
Project: Research
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3DTryp: Characterisation of Trypanosoma sequestration to endothelial cells
Pereira, S. S. (PI)
12/03/23 → 11/09/24
Project: Research
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Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration
Porqueddu, T., Zorrinho-Almeida, M., Niz, M. D., Casas-Sánchez, A., Introini, V., Sender, S. S., Carrasqueira, D., Figueiredo, L. M., Bernabeu, M. & Pereira, S. S., Dec 2025, In: Communications Biology. 8, 1, 15 p., 321.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads -
Investigation of Trypanosoma-induced vascular damage sheds insights into Trypanosoma vivax sequestration
Pereira, S. S., Brás, D., Porqueddu, T., Nascimento, A. M. & Niz, M. D., 15 Dec 2023, In: The Cell Surface. 10, 100113.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)29 Downloads -
Investigation of Trypanosoma-induced vascular damage sheds insights into Trypanosoma vivax sequestration
Pereira, S. S., Brás, D., Porqueddu, T., Nascimento, A. M. & Niz, M. D., 18 Sept 2023, 24 p.Research output: Working paper › Preprint
Open AccessFile24 Downloads -
Evolution of the variant surface glycoprotein family in African trypanosomes
Pereira, S. S., Jackson, A. P. & Figueiredo, L. M., Jan 2022, In: Trends in Parasitology. 38, 1, p. 23-36 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access19 Citations (Scopus) -
Immunopathology and Trypanosoma congolense parasite sequestration cause acute cerebral trypanosomiasis
Pereira, S. S., Niz, M. D., Serre, K., Ouarné, M., Coelho, J., Franco, C. A. & Figueiredo, L. M., Jul 2022, In: eLife. 11, e77440.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus)
Prizes
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2024 L'Oréal Portugal Medal of Honor for Women in Science
Pereira, S. S. (Recipient), 5 Jun 2024
Prize
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Press/Media
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E se a doença do sono chegar à Europa? Esta cientista estuda o parasita para o combater melhor — enquanto há tempo
23/09/24
1 Media contribution
Press/Media