Project Details
Description
Agro-food industries, e.g., fisheries and meet, generate large amounts of residues traditionally discarded. They are now recognized as a viable and low-cost source of biological compounds with high functionality for biomedical
applications. In this scenario, rabbit skin would be a valuable solution for skin tissue engineering approaches. It is an important agro-food by-product explored by the world-leader felting company Cortadoria Nacional de Pêlo, S.A., generated in more than 5tons/day. This company in collaboration with CBQF-UCP proposes the co-valorization of this by-product, which presents a unique opportunity to raise global awareness about the importance of skin care and to valorize rabbit skin as a sustainable resource for scientific innovation. Thus, STAR-SKIN aims to validate an acellular rabbit dermal matrix as a platform for three-dimensional (3D) human skin models development. To do so, three specific objectives will be outlined: 1) To create innovative acellular dermal matrices based on a agro-food by-product with similar architecture and biochemical features to human dermal skin; 2) To develop a highly preserved 3D matrix as platform for the development of human skin models. 3) Change the paradigm in processing biological tissues for biomedical applications at industrial scale
Therefore, STAR-SKIN represents a unique opportunity to use innovative decellularization methods and advanced biotechnology tools for the valorization of rabbit dermal matrix capable of being applied in skin tissue engineering industry and ultimately improve clinical practice.
applications. In this scenario, rabbit skin would be a valuable solution for skin tissue engineering approaches. It is an important agro-food by-product explored by the world-leader felting company Cortadoria Nacional de Pêlo, S.A., generated in more than 5tons/day. This company in collaboration with CBQF-UCP proposes the co-valorization of this by-product, which presents a unique opportunity to raise global awareness about the importance of skin care and to valorize rabbit skin as a sustainable resource for scientific innovation. Thus, STAR-SKIN aims to validate an acellular rabbit dermal matrix as a platform for three-dimensional (3D) human skin models development. To do so, three specific objectives will be outlined: 1) To create innovative acellular dermal matrices based on a agro-food by-product with similar architecture and biochemical features to human dermal skin; 2) To develop a highly preserved 3D matrix as platform for the development of human skin models. 3) Change the paradigm in processing biological tissues for biomedical applications at industrial scale
Therefore, STAR-SKIN represents a unique opportunity to use innovative decellularization methods and advanced biotechnology tools for the valorization of rabbit dermal matrix capable of being applied in skin tissue engineering industry and ultimately improve clinical practice.
Short title | STAR-SKIN |
---|---|
Acronym | STAR-SKIN |
Status | Active |
Effective start/end date | 1/09/24 → 28/02/26 |
Keywords
- Agro-food by-product
- Rabbit skin valorization
- Decellularized rabbit dermis
- 3D Human Skin models
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