A critical survey of predictive mathematical models for migration from packaging

Maria F. Poças, Jorge C. Oliveira, Fernanda A. R. Oliveira, Timothy Hogg

Research output: Contribution to journalReview articlepeer-review

76 Citations (Scopus)


The migration of chemicals from food contact materials into foods is an important issue in food safety. The assessment of materials compliance with regulations includes migration monitoring for many monomers and additives. However, it is recognized that predictive mathematical modelling can be used in many cases, to avoid or to reduce the effort on migration experiments. This article reviews the approaches followed to apply mathematical models to migration, particularly the models used, the approaches to estimate model parameters, and the systems used to experimentally validate the models. Conclusions on the issues requiring further research are drawn.
Original languageEnglish
Pages (from-to)913-928
Number of pages16
JournalCritical Reviews in Food Science and Nutrition
Issue number10
Publication statusPublished - Nov 2008


  • Diffusion coefficient
  • Fick's law
  • Partition coefficient
  • Plastic packaging
  • Probabilistic models


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