TY - JOUR
T1 - A critical survey of predictive mathematical models for migration from packaging
AU - Poças, Maria F.
AU - Oliveira, Jorge C.
AU - Oliveira, Fernanda A. R.
AU - Hogg, Timothy
PY - 2008/11
Y1 - 2008/11
N2 - The migration of chemicals from food contact materials into foods is an important issue in food safety. The assessment of materials compliance with regulations includes migration monitoring for many monomers and additives. However, it is recognized that predictive mathematical modelling can be used in many cases, to avoid or to reduce the effort on migration experiments. This article reviews the approaches followed to apply mathematical models to migration, particularly the models used, the approaches to estimate model parameters, and the systems used to experimentally validate the models. Conclusions on the issues requiring further research are drawn.
AB - The migration of chemicals from food contact materials into foods is an important issue in food safety. The assessment of materials compliance with regulations includes migration monitoring for many monomers and additives. However, it is recognized that predictive mathematical modelling can be used in many cases, to avoid or to reduce the effort on migration experiments. This article reviews the approaches followed to apply mathematical models to migration, particularly the models used, the approaches to estimate model parameters, and the systems used to experimentally validate the models. Conclusions on the issues requiring further research are drawn.
KW - Diffusion coefficient
KW - Fick's law
KW - Partition coefficient
KW - Plastic packaging
KW - Probabilistic models
UR - http://www.scopus.com/inward/record.url?scp=54849439984&partnerID=8YFLogxK
U2 - 10.1080/10408390701761944
DO - 10.1080/10408390701761944
M3 - Review article
C2 - 18949594
AN - SCOPUS:54849439984
SN - 1040-8398
VL - 48
SP - 913
EP - 928
JO - Critical Reviews in Food Science and Nutrition
JF - Critical Reviews in Food Science and Nutrition
IS - 10
ER -