A fast process for imprinting micro and nano patterns on electrospun fiber meshes at physiological temperatures

Anandkumar Nandakumar; Roman Truckenmüller; Maqsood Ahmed; Febriyani Damanik; Diogo Reis Santos; Nils Auffermann; Jan De Boer; Pamela Habibovic; Clemens Van Blitterswijk; Lorenzo Moroni

doi:10.1002/smll.201300220

A fast process for imprinting micro and nano patterns on electrospun fiber meshes at physiological temperatures

Anandkumar Nandakumar
, Roman Truckenmüller
, Maqsood Ahmed
, Febriyani Damanik
, Diogo Reis Santos
, Nils Auffermann
, Jan De Boer
, Pamela Habibovic
, Clemens Van Blitterswijk
, Lorenzo Moroni^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Electrospun fiber meshes are patterned at length scales comparable to or lower than their fiber diameter. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Human mesenchymal stromal cells cultured on patterned scaffolds show differences in cellular morphology and cytoskeleton organization. Microgrooved electrospun fibers support upregulation of alkaline phosphatase and bone morphogenetic protein-2 gene expression when cells are cultured in osteogenic medium.

Original language	English
Pages (from-to)	3405-3409
Number of pages	5
Journal	Small
Volume	9
Issue number	20
DOIs	https://doi.org/10.1002/smll.201300220
Publication status	Published - 25 Oct 2013

Keywords

Biomedical engineering
Electrospinning
Fibers
Patterning
Physiological temperatures

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title = "A fast process for imprinting micro and nano patterns on electrospun fiber meshes at physiological temperatures",

abstract = "Electrospun fiber meshes are patterned at length scales comparable to or lower than their fiber diameter. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Human mesenchymal stromal cells cultured on patterned scaffolds show differences in cellular morphology and cytoskeleton organization. Microgrooved electrospun fibers support upregulation of alkaline phosphatase and bone morphogenetic protein-2 gene expression when cells are cultured in osteogenic medium.",

keywords = "Biomedical engineering, Electrospinning, Fibers, Patterning, Physiological temperatures",

author = "Anandkumar Nandakumar and Roman Truckenm{\"u}ller and Maqsood Ahmed and Febriyani Damanik and Santos, \{Diogo Reis\} and Nils Auffermann and Boer, \{Jan De\} and Pamela Habibovic and Blitterswijk, \{Clemens Van\} and Lorenzo Moroni",

year = "2013",

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doi = "10.1002/smll.201300220",

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T1 - A fast process for imprinting micro and nano patterns on electrospun fiber meshes at physiological temperatures

AU - Nandakumar, Anandkumar

AU - Truckenmüller, Roman

AU - Ahmed, Maqsood

AU - Damanik, Febriyani

AU - Santos, Diogo Reis

AU - Auffermann, Nils

AU - Boer, Jan De

AU - Habibovic, Pamela

AU - Blitterswijk, Clemens Van

AU - Moroni, Lorenzo

PY - 2013/10/25

Y1 - 2013/10/25

N2 - Electrospun fiber meshes are patterned at length scales comparable to or lower than their fiber diameter. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Human mesenchymal stromal cells cultured on patterned scaffolds show differences in cellular morphology and cytoskeleton organization. Microgrooved electrospun fibers support upregulation of alkaline phosphatase and bone morphogenetic protein-2 gene expression when cells are cultured in osteogenic medium.

AB - Electrospun fiber meshes are patterned at length scales comparable to or lower than their fiber diameter. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Human mesenchymal stromal cells cultured on patterned scaffolds show differences in cellular morphology and cytoskeleton organization. Microgrooved electrospun fibers support upregulation of alkaline phosphatase and bone morphogenetic protein-2 gene expression when cells are cultured in osteogenic medium.

KW - Biomedical engineering

KW - Electrospinning

KW - Fibers

KW - Patterning

KW - Physiological temperatures

UR - https://www.scopus.com/pages/publications/84885987992

U2 - 10.1002/smll.201300220

DO - 10.1002/smll.201300220

M3 - Article

C2 - 23447336

AN - SCOPUS:84885987992

SN - 1613-6810

VL - 9

SP - 3405

EP - 3409

JO - Small

JF - Small

IS - 20

ER -

A fast process for imprinting micro and nano patterns on electrospun fiber meshes at physiological temperatures

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Keywords

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