Acute myeloid leukemia in the older adults

António M. Almeida, Fernando Ramos*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

88 Citations (Scopus)

Abstract

AML is an aggressive hematological malignancy with highest incidence in the older adults. The adverse features of AML in the elderly, and the frailties and comorbidities frequently present in them, make their management a particularly difficult therapeutic challenge. In this context, it is important to assess carefully patient- as well as disease-associated prognostic features with validated tools. The fittest patients should be considered for curative therapy, such as bone marrow transplantation, whereas low intensity options may be more appropriate for frail patients. Here we review how to assess patients with elderly AML and the treatments options available for them.
Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalLeukemia Research Reports
Volume6
DOIs
Publication statusPublished - 2016
Externally publishedYes

Keywords

  • Acute myeloid leukemia
  • Elderly
  • Geriatric assessment
  • Prognosis
  • Therapy

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