TY - CHAP
T1 - Alginate
T2 - pharmaceutical and medical applications
AU - Batista, Patrícia Sofia Pinhanços
AU - Morais, Alcina Maria Miranda Bernardo de
AU - Pintado, Maria Manuela Estevez
AU - Morais, Rui Manuel Santos Costa de
PY - 2019/1
Y1 - 2019/1
N2 - Due to their outstanding properties in terms of mild gelation conditions and simple functionalization, biocompatibility, low toxicity, biodegradability, non-antigenicity and chelating ability, as well as relatively low cost, alginates have been widely used in a variety of biomedical applications including tissue engineering and drug delivery systems. Smart alginate hydrogels for on-demand drug release in response to environmental stimuli and 3D bioprinting will play an important role in the future. These and the introduction of appropriate cell interactive features will be crucial for many tissue engineering applications. The focus of the present chapter is to highlight the great potential of the alginates as biomaterial for biomedical applications and to discuss the role that alginate-based materials are likely to play in biomedical applications in the future.
AB - Due to their outstanding properties in terms of mild gelation conditions and simple functionalization, biocompatibility, low toxicity, biodegradability, non-antigenicity and chelating ability, as well as relatively low cost, alginates have been widely used in a variety of biomedical applications including tissue engineering and drug delivery systems. Smart alginate hydrogels for on-demand drug release in response to environmental stimuli and 3D bioprinting will play an important role in the future. These and the introduction of appropriate cell interactive features will be crucial for many tissue engineering applications. The focus of the present chapter is to highlight the great potential of the alginates as biomaterial for biomedical applications and to discuss the role that alginate-based materials are likely to play in biomedical applications in the future.
U2 - 10.1007/978-3-030-12919-4_16
DO - 10.1007/978-3-030-12919-4_16
M3 - Chapter
SN - 9783030129187
T3 - Biologically-Inspired Systems
SP - 649
EP - 691
BT - Extracellular sugar-based biopolymers matrices
A2 - Cohen, Ephraim
A2 - Merzendorfer, Hans
PB - Springer Nature Switzerland AG
CY - Cham
ER -