Application of a high-throughput process analytical technology metabolomics pipeline to Port wine forced ageing process

Cristiana C. Castro, R. C. Martins, José A. Teixeira, António C. Silva Ferreira*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

Metabolomics aims at gathering the maximum amount of metabolic information for a total interpretation of biological systems. A process analytical technology pipeline, combining gas chromatography-mass spectrometry data preprocessing with multivariate analysis, was applied to a Port wine "forced ageing" process under different oxygen saturation regimes at 60 °C. It was found that extreme "forced ageing" conditions promote the occurrence of undesirable chemical reactions by production of dioxane and dioxolane isomers, furfural and 5-hydroxymethylfurfural, which affect the quality of the final product through the degradation of the wine aromatic profile, colour and taste. Also, were found high kinetical correlations between these key metabolites with benzaldehyde, sot-olon, and many other metabolites that contribute for the final aromatic profile of the Port wine. The use of the kinetical correlations in time-dependent processes as wine ageing can further contribute to biological or chemical systems monitoring, new biomarkers discovery and metabolic network investigations.
Original languageEnglish
Pages (from-to)384-391
Number of pages8
JournalFood Chemistry
Volume143
DOIs
Publication statusPublished - 2014

Keywords

  • Co-expression
  • Forced ageing
  • GC-MS
  • Multivariate analysis
  • Port wine

Fingerprint

Dive into the research topics of 'Application of a high-throughput process analytical technology metabolomics pipeline to Port wine forced ageing process'. Together they form a unique fingerprint.

Cite this