Assessment of baby Bibs. GC-MS screening, migration into saliva and insight of toxicity with QSAR tools

Chandisree Rajbux, Joel Pereira, Maria do Céu Selbourne, Ana Rita Costa-Pinto, Fátima Poças*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Plastic baby Bibs are, according to the European legislation, food contact materials. Therefore, compositional and migration limits applicable to plastics should be observed. This work aimed at identifying potential migrants in Bibs from European market and determining the migration into artificial saliva. Bibs were subjected to screening analyses (GC-MS). Thirty substances non-authorised in European or Swiss legislation were detected: phthalates, light stabilizers, flame retardants and photoinitiators. Irgacure 184, Cyclohexanone, Tinuvin 770, Isophorone and 9-Octadecenamide, (Z)- were detected in saliva after contact with selected Bibs. The migration values render two samples noncompliant although results should be interpreted with caution given the experimental conditions. In order to gain insight on the toxicity of migrants, QSAR tools were applied. Substances non-evaluated or not-listed were analysed with free software regarding their Cramer class ToxTree and their predicted mutagenicity, carcinogenicity and developmental toxicity (VEGA). Results indicate that surveillance is required: monitoring Bibs'compliance, application of GMPs and traceability.

Original languageEnglish
Article number106951
JournalFood Control
Volume109
DOIs
Publication statusPublished - Mar 2020

Keywords

  • Baby bibs
  • Food contact materials
  • Migration
  • NIAS
  • Plastics
  • QSAR
  • Safety evaluation

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