TY - CHAP
T1 - Biological activities of chitin, chitosan and respective oligomers
AU - Tavaria, Freni K.
AU - Fernandes, João
AU - Santos-Silva, Alice
AU - Silva, Sara Baptista da
AU - Sarmento, Bruno
AU - Pintado, Manuela
PY - 2011
Y1 - 2011
N2 - Chitin and chitosan have been receiving great attention as a novel functional material for their excellent biological properties such as biodegradation, immunological, antioxidant and antibacterial activities. However, its use has been scarcely developed due to its high molecular weight, which causes poor water solubility and high viscosity of the solutions. Compared with ordinary chitosan, chitosan oligomers have much improved water-solubility and some special biological functions due to the high absorption rate at the intestinal level, thus permitting its entrance in blood circulation and distribution all over the body. The potential application of chitin and chitosan, and respective oligomers, is multidimensional and it has been found in food and nutrition, biotechnology, material science, drug delivery, agriculture and environmental protection, and recently gene therapy too. In the realm of this chapter, we will focus on some biological activities attributed to those molecules, such as, antimicrobial and antifungal activities, wound healing, antioxidant, anti-inflammatory, anti-carcinogenic and anti-coagulant.
AB - Chitin and chitosan have been receiving great attention as a novel functional material for their excellent biological properties such as biodegradation, immunological, antioxidant and antibacterial activities. However, its use has been scarcely developed due to its high molecular weight, which causes poor water solubility and high viscosity of the solutions. Compared with ordinary chitosan, chitosan oligomers have much improved water-solubility and some special biological functions due to the high absorption rate at the intestinal level, thus permitting its entrance in blood circulation and distribution all over the body. The potential application of chitin and chitosan, and respective oligomers, is multidimensional and it has been found in food and nutrition, biotechnology, material science, drug delivery, agriculture and environmental protection, and recently gene therapy too. In the realm of this chapter, we will focus on some biological activities attributed to those molecules, such as, antimicrobial and antifungal activities, wound healing, antioxidant, anti-inflammatory, anti-carcinogenic and anti-coagulant.
UR - http://www.scopus.com/inward/record.url?scp=84895276854&partnerID=8YFLogxK
M3 - Chapter
AN - SCOPUS:84895276854
SN - 9781613244548
SP - 171
EP - 198
BT - Focus on chitosan research
PB - Nova Science Publishers, Inc.
ER -