TY - GEN
T1 - Carotid artery atherosclerosis plaque analysis using CT and histology
AU - Santos, F.
AU - Joutsen, A.
AU - Salenius, J.
AU - Eskola, H.
PY - 2012
Y1 - 2012
N2 - This research had its focus in the creation of a protocol able to diagnose atherosclerosis and to segment the atherosclerotic plaques into different tissue components. The protocol compared in vivo and in vitro Multidetector Computed Tomography (MDCT) with histology studies. Four patients composed the data set. After the plaque samples were extracted in carotid artery endarterectomy, they were cast in paraffin, imaged, sliced and stained for the histology study. ImageJ was used to draw by hand regions of interest around the plaque, and to obtain an auto-segmentation of the plaques and their components. The final results showed a correct correlation and representation of the atherosclerotic plaque between the different modalities. The protocol and methods used in this study were confirmed as a viable way of diagnostic and follow-up of the patients suffering from atherosclerosis in the carotid arteries.
AB - This research had its focus in the creation of a protocol able to diagnose atherosclerosis and to segment the atherosclerotic plaques into different tissue components. The protocol compared in vivo and in vitro Multidetector Computed Tomography (MDCT) with histology studies. Four patients composed the data set. After the plaque samples were extracted in carotid artery endarterectomy, they were cast in paraffin, imaged, sliced and stained for the histology study. ImageJ was used to draw by hand regions of interest around the plaque, and to obtain an auto-segmentation of the plaques and their components. The final results showed a correct correlation and representation of the atherosclerotic plaque between the different modalities. The protocol and methods used in this study were confirmed as a viable way of diagnostic and follow-up of the patients suffering from atherosclerosis in the carotid arteries.
UR - http://www.scopus.com/inward/record.url?scp=84856762367&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84856762367
SN - 9780415683951
T3 - Computational Vision and Medical Image Processing, Proceedings of VipIMAGE 2011 - 3rd ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing
SP - 261
EP - 265
BT - Computational Vision and Medical Image Processing, Proceedings of VipIMAGE 2011 - 3rd ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing
T2 - 3rd ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, VipIMAGE 2011
Y2 - 12 October 2011 through 14 October 2011
ER -