Characterization of the mechanical and biological properties of a new alumina scaffold

Patrícia S. P. Batista; Miguel A. A. Rodrigues; Daniela M. R. Silva; Patrícia I. C. Morgado; Joaquim P. Henriques; Maria O. Almeida; Abílio P. Silva; Ilídio J. Correia

doi:10.5301/jabfm.2012.9264

Characterization of the mechanical and biological properties of a new alumina scaffold

Patrícia S. P. Batista, Miguel A. A. Rodrigues, Daniela M. R. Silva, Patrícia I. C. Morgado, Joaquim P. Henriques, Maria O. Almeida, Abílio P. Silva, Ilídio J. Correia

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Purpose: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results: The results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. The in vivo studies revealed no systemic reaction. Conclusions: The alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.

Original language	English
Pages (from-to)	18-25
Number of pages	8
Journal	Journal of Applied Biomaterials and Functional Materials
Volume	11
Issue number	1
DOIs	https://doi.org/10.5301/jabfm.2012.9264
Publication status	Published - 2013
Externally published	Yes

Keywords

Alumina scaffolds
Biomedical applications
Bone regeneration
Ceramic biomaterials
Porosity
Sintering

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10.5301/jabfm.2012.9264

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title = "Characterization of the mechanical and biological properties of a new alumina scaffold",

abstract = "Purpose: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results: The results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. The in vivo studies revealed no systemic reaction. Conclusions: The alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.",

keywords = "Alumina scaffolds, Biomedical applications, Bone regeneration, Ceramic biomaterials, Porosity, Sintering",

author = "Batista, {Patr{\'i}cia S. P.} and Rodrigues, {Miguel A. A.} and Silva, {Daniela M. R.} and Morgado, {Patr{\'i}cia I. C.} and Henriques, {Joaquim P.} and Almeida, {Maria O.} and Silva, {Ab{\'i}lio P.} and Correia, {Il{\'i}dio J.}",

year = "2013",

doi = "10.5301/jabfm.2012.9264",

language = "English",

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T1 - Characterization of the mechanical and biological properties of a new alumina scaffold

AU - Batista, Patrícia S. P.

AU - Rodrigues, Miguel A. A.

AU - Silva, Daniela M. R.

AU - Morgado, Patrícia I. C.

AU - Henriques, Joaquim P.

AU - Almeida, Maria O.

AU - Silva, Abílio P.

AU - Correia, Ilídio J.

PY - 2013

Y1 - 2013

N2 - Purpose: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results: The results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. The in vivo studies revealed no systemic reaction. Conclusions: The alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.

AB - Purpose: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. Methods: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. Results: The results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. The in vivo studies revealed no systemic reaction. Conclusions: The alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.

KW - Alumina scaffolds

KW - Biomedical applications

KW - Bone regeneration

KW - Ceramic biomaterials

KW - Porosity

KW - Sintering

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JO - Journal of Applied Biomaterials and Functional Materials

JF - Journal of Applied Biomaterials and Functional Materials

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Characterization of the mechanical and biological properties of a new alumina scaffold

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Keywords

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