TY - JOUR
T1 - Chemical profile and bioactive properties of the essential oil isolated from Ammodaucus leucotrichus fruits growing in Sahara and its evaluation as a cosmeceutical ingredient
AU - Halla, Noureddine
AU - Heleno, Sandrina A.
AU - Costa, Patrícia
AU - Fernandes, Isabel P.
AU - Calhelha, Ricardo C.
AU - Boucherit, Kebir
AU - Rodrigues, Alírio Egídio
AU - Ferreira, Isabel C.F.R.
AU - Barreiro, Maria Filomena
N1 - Funding Information:
The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Program PT2020 for financial support to CIMO (UID/AGR/00690/2013), S.A. Heleno (SFRH/BPD/101413/2014) and P. Costa (SFRH/BPD/101413/2014). This work was also financially supported by Project POCI-01-0145-FEDER-006984–Associate Laboratory LSRE-LCM funded by FEDER through COMPETE 2020 – Programa Operacional Competitividade e Internacionalização (POCI) – and by national funds through FCT and project NORTE-01-0145-FEDER-000006 , supported by Norte Portugal Regional Operational Program (NORTE 2020) , under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF).
Funding Information:
The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Program PT2020 for financial support to CIMO (UID/AGR/00690/2013), S.A. Heleno (SFRH/BPD/101413/2014) and P. Costa (SFRH/BPD/101413/2014). This work was also financially supported by Project POCI-01-0145-FEDER-006984–Associate Laboratory LSRE-LCM funded by FEDER through COMPETE 2020 – Programa Operacional Competitividade e Internacionalização (POCI) – and by national funds through FCT and project NORTE-01-0145-FEDER-000006, supported by Norte Portugal Regional Operational Program (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF).
Publisher Copyright:
© 2018 Elsevier B.V.
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Ammodaucus leucotrichus is a medicinal plant commonly used in Algeria by the indigenous populations, especially due to its therapeutic effects. In this context, the aim of the present study was to chemically characterize the essential oil of A. leucotrichus fruits (EOALF) growing in Algerian Sahara, and to evaluate its bioactive properties (antimicrobial, antioxidant and anti-inflammatory). Considering the interest of the cosmetic industry for natural ingredients, and taking into account the obtained biological properties, the essential oil was also evaluated by incorporation in a base cosmetic (cream). The essential oil was extracted with a yield of 2.58 ± 0.17%, being perilla aldehyde identified as the main component, accounting for 85.6% of the total composition. Concerning the tested bioactivities, EOALF presented antioxidant potential, a strong anti-inflammatory activity, and was effective against the tested microbial strains (Staphylococcus aureus, Eschericia coli and Pseudomonas aeruginosa), being S. aureus the most sensitive bacteria. After incorporation in a base cosmetic, the developed formulation was able to preserve the EOALF bioactivities along 28 days under storage. The obtained results, with relevance for the strong-anti-inflammatory activity, pointed out the interest to exploit this essential oil as a cosmeceutical ingredient in the cosmetic industry.
AB - Ammodaucus leucotrichus is a medicinal plant commonly used in Algeria by the indigenous populations, especially due to its therapeutic effects. In this context, the aim of the present study was to chemically characterize the essential oil of A. leucotrichus fruits (EOALF) growing in Algerian Sahara, and to evaluate its bioactive properties (antimicrobial, antioxidant and anti-inflammatory). Considering the interest of the cosmetic industry for natural ingredients, and taking into account the obtained biological properties, the essential oil was also evaluated by incorporation in a base cosmetic (cream). The essential oil was extracted with a yield of 2.58 ± 0.17%, being perilla aldehyde identified as the main component, accounting for 85.6% of the total composition. Concerning the tested bioactivities, EOALF presented antioxidant potential, a strong anti-inflammatory activity, and was effective against the tested microbial strains (Staphylococcus aureus, Eschericia coli and Pseudomonas aeruginosa), being S. aureus the most sensitive bacteria. After incorporation in a base cosmetic, the developed formulation was able to preserve the EOALF bioactivities along 28 days under storage. The obtained results, with relevance for the strong-anti-inflammatory activity, pointed out the interest to exploit this essential oil as a cosmeceutical ingredient in the cosmetic industry.
KW - Ammodaucus leucotrichus
KW - Bioactivity
KW - Cosmeceuticals
KW - Essential oils
KW - Preservers
UR - http://www.scopus.com/inward/record.url?scp=85045710479&partnerID=8YFLogxK
U2 - 10.1016/j.indcrop.2018.04.043
DO - 10.1016/j.indcrop.2018.04.043
M3 - Article
AN - SCOPUS:85045710479
SN - 0926-6690
VL - 119
SP - 249
EP - 254
JO - Industrial Crops and Products
JF - Industrial Crops and Products
ER -