Abstract
This chapter contains sections titled: Introduction Challenges on the Oral Delivery of Therapeutic Proteins Challenges on the Oral Delivery of Genetic Material Role of Chitosan in the Protection of Biopharmaceuticals in the Gastrointestinal Tract Chitosan-Based Nanoparticles for Oral Delivery of Therapeutic Proteins Chitosan-Based Nanoparticles for Oral Delivery of Genetic Material Conclusions and Future Perspectives Acknowledgments References
Original language | English |
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Number of pages | 17 |
DOIs | |
Publication status | Published - 17 Feb 2012 |
Externally published | Yes |
Keywords
- And clinically relevant oral bioavailability
- Biopharmaceutical drugs
- Cationic polymers
- Chitosan
- Chitosan role in biopharmaceutical protection
- Chitosan-based nanoparticles for oral delivery
- Chitosan-based nanoparticulates
- Chitosans
- Gene therapy
- Hindered by high MW
- Iin replacing defective genes
- In oral delivery
- Major challenge in terms of formulation
- Oral absorption of biopharmaceuticals
- PEI
- Perfectly mastered
- Protecting genetic material from GI
- Technology of chitosan-based nanosystems
- poly(L-lysine)