Chitosan-Based Nanoparticulates for Oral Delivery of Biopharmaceuticals

Research output: Other contributionpeer-review

3 Citations (Scopus)

Abstract

This chapter contains sections titled: Introduction Challenges on the Oral Delivery of Therapeutic Proteins Challenges on the Oral Delivery of Genetic Material Role of Chitosan in the Protection of Biopharmaceuticals in the Gastrointestinal Tract Chitosan-Based Nanoparticles for Oral Delivery of Therapeutic Proteins Chitosan-Based Nanoparticles for Oral Delivery of Genetic Material Conclusions and Future Perspectives Acknowledgments References

Original languageEnglish
Number of pages17
DOIs
Publication statusPublished - 17 Feb 2012
Externally publishedYes

Keywords

  • And clinically relevant oral bioavailability
  • Biopharmaceutical drugs
  • Cationic polymers
  • Chitosan
  • Chitosan role in biopharmaceutical protection
  • Chitosan-based nanoparticles for oral delivery
  • Chitosan-based nanoparticulates
  • Chitosans
  • Gene therapy
  • Hindered by high MW
  • Iin replacing defective genes
  • In oral delivery
  • Major challenge in terms of formulation
  • Oral absorption of biopharmaceuticals
  • PEI
  • Perfectly mastered
  • Protecting genetic material from GI
  • Technology of chitosan-based nanosystems
  • poly(L-lysine)

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