TY - JOUR
T1 - Chitosan impregnated gutta-percha points
T2 - antimicrobial in vitro evaluation and mechanical properties
AU - Cardelle-Cobas, Alejandra
AU - Reis, Patrícia J. M.
AU - Costa, Eduardo
AU - Tavaria, Freni K.
AU - Pintado, Manuela E.
N1 - Funding Information:
This project was funded under the Project – Quitoral: development of new chitosan formulations for application in oral medicine [QREN-ADI 3474]. Financial support for A. Cardelle-Cobas was obtained via Fundac¸ão para a Ciência e Tecnologia (FCT, Portugal) through a postdoctoral grant [SFRH/BPD/90069/2012].
Funding Information:
This project was funded under the Project?Quitoral: development of new chitosan formulations for application in oral medicine [QREN-ADI 3474]. Financial support for A. Cardelle-Cobas was obtained via Funda??o para a Ci?ncia e Tecnologia (FCT, Portugal) through a postdoctoral grant [SFRH/BPD/90069/2012]. We would like to thank the scientific collaboration of CBQF under the FCT project UID/Multi/50016/2013.
Publisher Copyright:
© 2018, © 2018 Taylor & Francis.
PY - 2019/6/13
Y1 - 2019/6/13
N2 - Chitosan-impregnated gutta-percha points (ChitGPP) were tested for their ability to inhibit the growth of microorganisms usually involved in root canal infections. Their mechanical properties were also studied and compared with the commonly used commercial points in endodontics. ChitGPP were more efficient in reducing the microbial load than those without chitosan. ChitGPP also possess better tensile and elastic properties than commercial ones. After six months of storage, ChitGPP’s were still able to reduce the bacterial load by 1 log, suggesting that impregnation of gutta-percha points with chitosan could be a good alternative to obtain gutta-percha points with improved antimicrobial properties.
AB - Chitosan-impregnated gutta-percha points (ChitGPP) were tested for their ability to inhibit the growth of microorganisms usually involved in root canal infections. Their mechanical properties were also studied and compared with the commonly used commercial points in endodontics. ChitGPP were more efficient in reducing the microbial load than those without chitosan. ChitGPP also possess better tensile and elastic properties than commercial ones. After six months of storage, ChitGPP’s were still able to reduce the bacterial load by 1 log, suggesting that impregnation of gutta-percha points with chitosan could be a good alternative to obtain gutta-percha points with improved antimicrobial properties.
KW - Antimicrobial activity
KW - Chitosan
KW - Endodontic treatment
KW - Gutta-percha
KW - Mechanical properties
KW - Root canal filling materials
UR - http://www.scopus.com/inward/record.url?scp=85049558185&partnerID=8YFLogxK
U2 - 10.1080/00914037.2018.1466134
DO - 10.1080/00914037.2018.1466134
M3 - Article
AN - SCOPUS:85049558185
SN - 0091-4037
VL - 68
SP - 481
EP - 488
JO - International Journal of Polymeric Materials and Polymeric Biomaterials
JF - International Journal of Polymeric Materials and Polymeric Biomaterials
IS - 9
ER -