Abstract
Porphyrins have already demonstrated its potentiality in several scientific areas, with emphasis to
medicinal applications, like Photodynamic Therapy (PDT). Over the last years, the efforts to develop methods
able to convert porphyrins in new derivatives with adequate structural and spectroscopic characteristics to
become efficient PDT photosensitizers have been outstanding. In this work we review chlorins role in PDT as
well as synthesis of these derivatives, always taking into account its potential to be therapeutically used as
agents against cancer.
medicinal applications, like Photodynamic Therapy (PDT). Over the last years, the efforts to develop methods
able to convert porphyrins in new derivatives with adequate structural and spectroscopic characteristics to
become efficient PDT photosensitizers have been outstanding. In this work we review chlorins role in PDT as
well as synthesis of these derivatives, always taking into account its potential to be therapeutically used as
agents against cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 92-103 |
| Journal | Revista Virtual de Quimica |
| Publication status | Published - 2009 |
