TY - JOUR
T1 - Clinical and radiological outcomes for guided implant placement in sites preserved with bioactive glass bone graft after tooth extraction
T2 - a controlled clinical trial
AU - Baskaran, Priyanka
AU - Prakash, P. S.G.
AU - Appukuttan, Devapriya
AU - Mugri, Maryam H.
AU - Sayed, Mohammed
AU - Subramanian, Sangeetha
AU - Al Wadei, Mohammed Hussain Dafer
AU - Ahmed, Zeeshan Heera
AU - Dewan, Harisha
AU - Porwal, Amit
AU - Balaji, Thodur Madapusi
AU - Varadarajan, Saranya
AU - Heboyan, Artak
AU - Fernandes, Gustavo V. O.
AU - Patil, Shankargouda
N1 - Funding Information:
The authors thank the radiographic parameter assessor (A. Kannan, MDS) from the Department of Oral Medicine and Radiology, SRM Dental College, Ramapuram, Chennai, for his valuable support and help during the clinical trial.
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/6
Y1 - 2022/6
N2 - The goal of the study was to evaluate marginal bone loss (MBL) after 1-year implant placement using a guided implant surgical (GIS) protocol in grafted sockets compared to non-grafted sites. We followed a parallel study design with patients divided into two groups: grafted group (Test group, n = 10) and non-grafted group (Control, n = 10). A bioactive glass bone graft was used for grafting. A single edentulous site with a minimum bone height ≥11 mm and bone width ≥6 mm confirmed by cone-beam computerized tomography (CBCT) was chosen for implant placement. Tapered hybrid implants that were sandblasted and acid-etched (HSA) were placed using the GIS protocol and immediately loaded with a provisional prosthesis. MBL and implant survival rates (ISR) were assessed based on standardized radiographs and clinical exams. Patients were followed up for 1-year post-loading. MBL after one year, in the control group, was −0.31 mm ± 0.11 mm (me-sial) and −0.28 mm ± 0.09 mm (distal); and in the test group was −0.35 mm ± 0.11 mm (mesial) and −0.33 mm ± 0.13 mm (distal), with no statistical significance (p > 0.05). ISR was 100% in both groups after one year. ISR was similar between groups and the marginal bone changes were comparable one year after functional loading, without statistical significance, suggesting that bioactive glass permitted adequate bone formation. The GIS protocol avoided raising flaps and provided a better position to place implants, preserving the marginal bone around implants.
AB - The goal of the study was to evaluate marginal bone loss (MBL) after 1-year implant placement using a guided implant surgical (GIS) protocol in grafted sockets compared to non-grafted sites. We followed a parallel study design with patients divided into two groups: grafted group (Test group, n = 10) and non-grafted group (Control, n = 10). A bioactive glass bone graft was used for grafting. A single edentulous site with a minimum bone height ≥11 mm and bone width ≥6 mm confirmed by cone-beam computerized tomography (CBCT) was chosen for implant placement. Tapered hybrid implants that were sandblasted and acid-etched (HSA) were placed using the GIS protocol and immediately loaded with a provisional prosthesis. MBL and implant survival rates (ISR) were assessed based on standardized radiographs and clinical exams. Patients were followed up for 1-year post-loading. MBL after one year, in the control group, was −0.31 mm ± 0.11 mm (me-sial) and −0.28 mm ± 0.09 mm (distal); and in the test group was −0.35 mm ± 0.11 mm (mesial) and −0.33 mm ± 0.13 mm (distal), with no statistical significance (p > 0.05). ISR was 100% in both groups after one year. ISR was similar between groups and the marginal bone changes were comparable one year after functional loading, without statistical significance, suggesting that bioactive glass permitted adequate bone formation. The GIS protocol avoided raising flaps and provided a better position to place implants, preserving the marginal bone around implants.
KW - Bioactive glass
KW - CBCT
KW - Dental implants
KW - Flapless technique guided implant surgery
KW - Implant planning
KW - Minimally invasive surgical technique
KW - Surgical guides
UR - http://www.scopus.com/inward/record.url?scp=85129203568&partnerID=8YFLogxK
U2 - 10.3390/biomimetics7020043
DO - 10.3390/biomimetics7020043
M3 - Article
C2 - 35466260
AN - SCOPUS:85129203568
SN - 2313-7673
VL - 7
JO - Biomimetics
JF - Biomimetics
IS - 2
M1 - 43
ER -