Cytotoxic and antibacterial activity of chichá gum hydrogel associated with nerolidol

Idglan Sá Lima; Maria Onaira Gonçalves Ferreira; Albert Santos Silva; Alessandra Braga Ribeiro; Humberto Medeiros Barreto; Josy Anteveli Osajima  Furtini; Edson Cavalcanti da Silva Filho

Cytotoxic and antibacterial activity of chichá gum hydrogel associated with nerolidol

Idglan Sá Lima, Maria Onaira Gonçalves Ferreira, Albert Santos Silva, Alessandra Braga Ribeiro, Humberto Medeiros Barreto, Josy Anteveli Osajima Furtini, Edson Cavalcanti da Silva Filho^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Abstract

Chichá gum is a polysaccharide from the Sterculia striata plant, with a chemical structure composed of hydroxyl groups, which favor the formation of hydrogels, enabling the association with other materials to improve their biological properties and as drug delivery systems. Hydrogels were produced from chichá gum associated with nerolidol in concentrations of 1 and 2%, cytotoxicity was evaluated against Artemia salina. The hydrogels were tested against the strains Staphylococcus aureus and Escherichia coli, by the direct contact test. the material showed no toxic activity and an antibacterial effect was observed with 83.6% growth inhibition with the use of the hydrogel with 2% nerolidol. It concludes that the materials produced have the potential to be used in the future as products with good antibacterial properties.

Original language	English
Title of host publication	16th Brazilian Polymer Conference
Subtitle of host publication	proceedings
Pages	1-4
Number of pages	4
Publication status	Published - Oct 2021
Event	16th Brazilian Polymer Conference - Ouro Preto, Brazil Duration: 24 Oct 2021 → 28 Oct 2021 https://www.cbpol.com.br/

Conference

Conference	16th Brazilian Polymer Conference
Country/Territory	Brazil
City	Ouro Preto
Period	24/10/21 → 28/10/21
Internet address	https://www.cbpol.com.br/

Keywords

Antimicrobial
Polymer
Toxicity

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Cite this

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title = "Cytotoxic and antibacterial activity of chich{\'a} gum hydrogel associated with nerolidol",

abstract = "Chich{\'a} gum is a polysaccharide from the Sterculia striata plant, with a chemical structure composed of hydroxyl groups, which favor the formation of hydrogels, enabling the association with other materials to improve their biological properties and as drug delivery systems. Hydrogels were produced from chich{\'a} gum associated with nerolidol in concentrations of 1 and 2%, cytotoxicity was evaluated against Artemia salina. The hydrogels were tested against the strains Staphylococcus aureus and Escherichia coli, by the direct contact test. the material showed no toxic activity and an antibacterial effect was observed with 83.6% growth inhibition with the use of the hydrogel with 2% nerolidol. It concludes that the materials produced have the potential to be used in the future as products with good antibacterial properties.",

keywords = "Antimicrobial, Polymer, Toxicity",

author = "{S{\'a} Lima}, Idglan and Ferreira, {Maria Onaira Gon{\c c}alves} and Silva, {Albert Santos} and Ribeiro, {Alessandra Braga} and Barreto, {Humberto Medeiros} and Furtini, {Josy Anteveli Osajima} and Filho, {Edson Cavalcanti da Silva}",

year = "2021",

month = oct,

language = "English",

isbn = "9788563273444",

pages = "1--4",

booktitle = "16th Brazilian Polymer Conference",

note = "16th Brazilian Polymer Conference ; Conference date: 24-10-2021 Through 28-10-2021",

url = "https://www.cbpol.com.br/",

}

TY - GEN

T1 - Cytotoxic and antibacterial activity of chichá gum hydrogel associated with nerolidol

AU - Sá Lima, Idglan

AU - Ferreira, Maria Onaira Gonçalves

AU - Silva, Albert Santos

AU - Ribeiro, Alessandra Braga

AU - Barreto, Humberto Medeiros

AU - Furtini, Josy Anteveli Osajima

AU - Filho, Edson Cavalcanti da Silva

PY - 2021/10

Y1 - 2021/10

N2 - Chichá gum is a polysaccharide from the Sterculia striata plant, with a chemical structure composed of hydroxyl groups, which favor the formation of hydrogels, enabling the association with other materials to improve their biological properties and as drug delivery systems. Hydrogels were produced from chichá gum associated with nerolidol in concentrations of 1 and 2%, cytotoxicity was evaluated against Artemia salina. The hydrogels were tested against the strains Staphylococcus aureus and Escherichia coli, by the direct contact test. the material showed no toxic activity and an antibacterial effect was observed with 83.6% growth inhibition with the use of the hydrogel with 2% nerolidol. It concludes that the materials produced have the potential to be used in the future as products with good antibacterial properties.

AB - Chichá gum is a polysaccharide from the Sterculia striata plant, with a chemical structure composed of hydroxyl groups, which favor the formation of hydrogels, enabling the association with other materials to improve their biological properties and as drug delivery systems. Hydrogels were produced from chichá gum associated with nerolidol in concentrations of 1 and 2%, cytotoxicity was evaluated against Artemia salina. The hydrogels were tested against the strains Staphylococcus aureus and Escherichia coli, by the direct contact test. the material showed no toxic activity and an antibacterial effect was observed with 83.6% growth inhibition with the use of the hydrogel with 2% nerolidol. It concludes that the materials produced have the potential to be used in the future as products with good antibacterial properties.

KW - Antimicrobial

KW - Polymer

KW - Toxicity

M3 - Conference contribution

SN - 9788563273444

SP - 1

EP - 4

BT - 16th Brazilian Polymer Conference

T2 - 16th Brazilian Polymer Conference

Y2 - 24 October 2021 through 28 October 2021

ER -

Cytotoxic and antibacterial activity of chichá gum hydrogel associated with nerolidol

Abstract

Conference

Keywords

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