Data integration solution for organ-specific studies: an application for oral biology

José Melo, Joel P. Arrais, Edgar Coelho, Pedro Lopes, Nuno Rosa, Maria José Correia, Marlene Barros, José Luís Oliveira

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

The human oral cavity is a complex ecosystem where multiple interactions occur and whose comprehension is critical in understanding several disease mechanisms. In order to comprehend the composition of the oral cavity at a molecular level, it is necessary to compile and integrate the biological information resulting from specific techniques, especially from proteomic studies of saliva. The objective of this work was to compile and curate a specific group of proteins related to the oral cavity, providing a tool to conduct further studies of the salivary proteome. In this paper we present a platform that integrates in a single endpoint all available information for proteins associated with the oral cavity. The proposed tool allows researchers in biomedical sciences to explore microorganisms, proteins and diseases, constituting a unique tool to analyse meaningful interactions for oral health.
Original languageEnglish
Title of host publicationBiomedical Engineering Systems and Technologies - 5th International Joint Conference, BIOSTEC 2012, Revised Selected Papers
EditorsJoaquim Gabriel, Jan Schier, Sabine Van Huffel, Emmanuel Conchon, Carlos Correia, Ana Fred, Hugo Gamboa
Place of PublicationBerlin
PublisherSpringer Verlag
Pages401-412
Number of pages12
ISBN (Electronic)9783642382567
ISBN (Print)9783642382550
DOIs
Publication statusPublished - 2013
Event5th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2012 - Vilamoura, Algarve, Portugal
Duration: 1 Feb 20124 Feb 2012

Publication series

NameCommunications in Computer and Information Science
Volume357 CCIS
ISSN (Print)1865-0929
ISSN (Electronic)1865-0937

Conference

Conference5th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2012
Country/TerritoryPortugal
CityVilamoura, Algarve
Period1/02/124/02/12

Keywords

  • Data integration
  • Diseases
  • Oral health
  • Proteins
  • Web services

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