@article{4b25ba8fde984e91bb6239f89651a548,
title = "Detection of the crystallization process of paracetamol with a multi-mode optical fiber in a reflective configuration",
abstract = "A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% v/v of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.",
keywords = "Crystallization, Multi-mode optical fiber, Paracetamol",
author = "Liliana Soares and Susana Novais and Ant{\'o}nio Ferreira and Orlando Fraz{\~a}o and Susana Silva",
note = "Funding Information: Funding: This work is financed by: (I) the ERDF–European Regional Development Fund through the Operational Programme for Competitiveness and Internationalization–COMPETE 2020 Programme, and by National Funds through the Portuguese funding agency, FCT–Funda{\c c}{\~a}o para a Ci{\^e}ncia e a Tecnologia within project ENDOR–Endoscope based on New Optical Fibre Technology for Raman Spectroscopy (POCI-01-0145-FEDER-029724). (II) Project PTDC/QEQ-PRS/3787/2014–POCI-01-0145-FEDER-016816, funded by ERDF through COMPETE 2020–Programa Operacional Competitividade e Internacionaliza{\c c}{\~a}o (POCI) and by national funds through FCT–Project 9471, Refor{\c c}ar a Investiga{\c c}{\~a}o, o Desenvolvimento Tecnol{\'o}gico e a Inova{\c c}{\~a}o. III) IF exploratory project [IF/01087/2014] funded by FCT. Funding Information: This work is financed by: (I) the ERDF?European Regional Development Fund through the Operational Programme for Competitiveness and Internationalization?COMPETE 2020 Programme, and by National Funds through the Portuguese funding agency, FCT?Funda??o para a Ci?ncia e a Tecnologia within project ENDOR?Endoscope based on New Optical Fibre Technology for Raman Spectroscopy (POCI-01-0145-FEDER-029724). (II) Project PTDC/QEQ-PRS/3787/2014?POCI-01-0145-FEDER-016816, funded by ERDF through COMPETE 2020?Programa Operacional Competitividade e Internacionaliza??o (POCI) and by national funds through FCT?Project 9471, Refor?ar a Investiga??o, o Desenvolvimento Tecnol?gico e a Inova??o. III) IF exploratory project [IF/01087/2014] funded by FCT. Publisher Copyright: {\textcopyright} 2019 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2020",
month = jan,
day = "1",
doi = "10.3390/s20010087",
language = "English",
volume = "20",
journal = "Sensors (Switzerland)",
issn = "1424-8220",
publisher = "MDPI",
number = "1",
}