Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications

Chou I Ho; Francisco A. P. Rodrigues; Mariana S. Reis; Viviana P. Ribeiro; Ana Leite Oliveira; João B. Costa

doi:10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2

Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications

^*Corresponding author for this work

Research output: Contribution to conference › Poster

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Abstract

Introduction & Objectives Meniscal injuries occur approximately 66 to 70 per 100,000 individuals annually (Fig. 1), potentially leading to the development of osteoarthritis (OA) or other degenerative cartilage disease in 10 to 20 years. One of the conventional treatments is meniscal allograft transplantation. However, its limitations constrain its comprehensive application in the healthcare system.

Original language	English
Number of pages	1
DOIs	https://doi.org/10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2
Publication status	Published - Jun 2025
Event	33rd Annual Meeting of the European Orthopaedic Research Society (EORS) - Davos, Switzerland Duration: 16 Jun 2025 → 19 Jun 2025

Conference

Conference	33rd Annual Meeting of the European Orthopaedic Research Society (EORS)
Abbreviated title	EORS 2025
Country/Territory	Switzerland
City	Davos
Period	16/06/25 → 19/06/25

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10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2Licence: Unspecified

122455792Final published version, 5.61 MBLicence: Unspecified

http://hdl.handle.net/10400.14/53821Licence: Unspecified

CBQF - Centre for Biotecnology and Fine Chemistry: UID/50016/2025. Pluriannual 2025-2029
Pintado, M. M. (PI)
Fundação para a Ciência e a Tecnologia
1/01/25 → 31/12/29
Project: Research

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Ho, C. I., Rodrigues, F. A. P., Reis, M. S., Ribeiro, V. P., Oliveira, A. L., & Costa, J. B. (2025). Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications. Poster session presented at 33rd Annual Meeting of the European Orthopaedic Research Society (EORS) , Davos, Switzerland. https://doi.org/10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2

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title = "Detergent-free supercritical CO2{\textendash}assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications",

abstract = "Introduction \& Objectives Meniscal injuries occur approximately 66 to 70 per 100,000 individuals annually (Fig. 1), potentially leading to the development of osteoarthritis (OA) or other degenerative cartilage disease in 10 to 20 years. One of the conventional treatments is meniscal allograft transplantation. However, its limitations constrain its comprehensive application in the healthcare system.",

author = "Ho, \{Chou I\} and Rodrigues, \{Francisco A. P.\} and Reis, \{Mariana S.\} and Ribeiro, \{Viviana P.\} and Oliveira, \{Ana Leite\} and Costa, \{Jo{\~a}o B.\}",

year = "2025",

month = jun,

doi = "10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2",

language = "English",

note = " 33rd Annual Meeting of the European Orthopaedic Research Society (EORS) , EORS 2025 ; Conference date: 16-06-2025 Through 19-06-2025",

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Ho, CI , Rodrigues, FAP , Reis, MS , Ribeiro, VP , Oliveira, AL & Costa, JB 2025, 'Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications', 33rd Annual Meeting of the European Orthopaedic Research Society (EORS) , Davos, Switzerland, 16/06/25 - 19/06/25. https://doi.org/10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2

Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications. / Ho, Chou I ; Rodrigues, Francisco A. P.; Reis, Mariana S. et al.
2025. Poster session presented at 33rd Annual Meeting of the European Orthopaedic Research Society (EORS) , Davos, Switzerland.

Research output: Contribution to conference › Poster

TY - CONF

T1 - Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications

AU - Ho, Chou I

AU - Rodrigues, Francisco A. P.

AU - Reis, Mariana S.

AU - Ribeiro, Viviana P.

AU - Oliveira, Ana Leite

AU - Costa, João B.

PY - 2025/6

Y1 - 2025/6

N2 - Introduction & Objectives Meniscal injuries occur approximately 66 to 70 per 100,000 individuals annually (Fig. 1), potentially leading to the development of osteoarthritis (OA) or other degenerative cartilage disease in 10 to 20 years. One of the conventional treatments is meniscal allograft transplantation. However, its limitations constrain its comprehensive application in the healthcare system.

AB - Introduction & Objectives Meniscal injuries occur approximately 66 to 70 per 100,000 individuals annually (Fig. 1), potentially leading to the development of osteoarthritis (OA) or other degenerative cartilage disease in 10 to 20 years. One of the conventional treatments is meniscal allograft transplantation. However, its limitations constrain its comprehensive application in the healthcare system.

U2 - 10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2

DO - 10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2

M3 - Poster

T2 - 33rd Annual Meeting of the European Orthopaedic Research Society (EORS)

Y2 - 16 June 2025 through 19 June 2025

ER -

Ho CI , Rodrigues FAP , Reis MS , Ribeiro VP , Oliveira AL , Costa JB. Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications. 2025. Poster session presented at 33rd Annual Meeting of the European Orthopaedic Research Society (EORS) , Davos, Switzerland. doi: 10.34632/d2fa204f-e16b-4b86-9b46-9afa292368e2

Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications

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Projects

CBQF - Centre for Biotecnology and Fine Chemistry: UID/50016/2025. Pluriannual 2025-2029

Cite this