Development and validation of automatic HS-SPME with a gas chromatography-ion trap/mass spectrometry method for analysis of volatiles in wines

Nathalie Moreira, Giuliano Elias Pereira, Selma Gomes Ferreira Leite, Claudia Moraes Rezende, Paula Guedes de Pinho

Research output: Contribution to journalArticlepeer-review

91 Citations (Scopus)

Abstract

An automated headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-ion trap/mass spectrometry (GC-IT/MS) was developed in order to quantify a large number of volatile compounds in wines such as alcohols, ester, norisoprenoids and terpenes. The procedures were optimized for SPME fiber selection, pre-incubation temperature and time, extraction temperature and time, and salt addition. A central composite experimental design was used in the optimization of the extraction conditions. The volatile compounds showed optimal extraction using a DVB/CAR/PDMS fiber, incubation of 5 ml of wine with 2 g NaCl at 45 °C during 5 min, and subsequent extraction of 30 min at the same temperature. The method allowed the identification of 64 volatile compounds. Afterwards, the method was validated successfully for the most significant compounds and was applied to study the volatile composition of different white wines.
Original languageEnglish
Pages (from-to)177-186
Number of pages10
JournalTalanta
Volume101
DOIs
Publication statusPublished - 15 Nov 2012

Keywords

  • Central composite design
  • Gas chromatography-Ion Trap/Mass Spectrometry (GC-IT/MS)
  • Headspace solid-phase microextraction (HS-SPME)
  • Volatile compounds
  • Wine

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