TY - JOUR
T1 - Differential activation of the default mode network in jet lagged individuals
AU - Coutinho, Joana Fernandes
AU - Gonçalves, Oscar Filipe
AU - Maia, Liliana
AU - Vasconcelos, Cristiana Fernandes
AU - Perrone-McGovern, Kristin
AU - Simon-Dack, Stephanie
AU - Hernandez, Kristina
AU - Oliveira-Silva, Patricia
AU - Mesquita, Ana Raquel
AU - Sampaio, Adriana
N1 - Funding Information:
This study was funded by the Portuguese Foundation for Science and Technology (FCT): PIC/IC/83290/2007, which is supported by FEDER (POFC – COMPETE). Joana Coutinho was funded by a FCT postdoctoral grant (number: SFRH/BPD/75014/2010) and Bial Foundation (grant number 87/12). Liliana Maia is supported by the Competitive Factors Operational Programme – COMPETE – by national funds from the Portuguese Foundation for Science and Technology (grant PTDC/ PSI-PCL/115316/2009).
Publisher Copyright:
© 2015 Informa Healthcare USA, Inc.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2015/2/1
Y1 - 2015/2/1
N2 - Long-term exposure to transmeridian flights has been shown to impact cognitive functioning. Nevertheless, the immediate effects of jet lag in the activation of specific brain networks have not been investigated. We analyzed the impact of short-term jet lag on the activation of the default mode network (DMN). A group of individuals who were on a transmeridian flight and a control group went through a functional magnetic resonance imaging acquisition. Statistical analysis was performed to test for differences in the DMN activation between groups. Participants from the jet lag group presented decreased activation in the anterior nodes of the DMN, specifically in bilateral medial prefrontal and anterior cingulate cortex. No areas of increased activation were observed for the jet lag group. These results may be suggestive of a negative impact of jet lag on important cognitive functions such as introspection, emotional regulation and decision making in a few days after individuals arrive at their destination.
AB - Long-term exposure to transmeridian flights has been shown to impact cognitive functioning. Nevertheless, the immediate effects of jet lag in the activation of specific brain networks have not been investigated. We analyzed the impact of short-term jet lag on the activation of the default mode network (DMN). A group of individuals who were on a transmeridian flight and a control group went through a functional magnetic resonance imaging acquisition. Statistical analysis was performed to test for differences in the DMN activation between groups. Participants from the jet lag group presented decreased activation in the anterior nodes of the DMN, specifically in bilateral medial prefrontal and anterior cingulate cortex. No areas of increased activation were observed for the jet lag group. These results may be suggestive of a negative impact of jet lag on important cognitive functions such as introspection, emotional regulation and decision making in a few days after individuals arrive at their destination.
KW - Brain
KW - Default mode network
KW - Jet lag
UR - http://www.scopus.com/inward/record.url?scp=84921732498&partnerID=8YFLogxK
U2 - 10.3109/07420528.2014.955187
DO - 10.3109/07420528.2014.955187
M3 - Article
C2 - 25180985
AN - SCOPUS:84921732498
SN - 0742-0528
VL - 32
SP - 143
EP - 149
JO - Chronobiology International
JF - Chronobiology International
IS - 1
ER -