@article{471c0f94a312422b90949f219a51715d,
title = "Enantioseparation of chiral pharmaceuticals in biomedical and environmental analyses by liquid chromatography: an overview",
abstract = "This review aims to present the issues associated to enantioseparation of chiral pharmaceuticals in biological and environmental matrices using chiral stationary phases (CSP). Thus, it related some enantioselective methods in liquid chromatography (LC) and compares the importance given to chiral separation in biomedical and environmental fields. For that the most used CSP, the enantioselective chromatographic methods, their advantages and drawbacks were swiftly revised and compared. The recent advances and the limitations of chiral analytical methods in LC were also discussed.",
keywords = "Biological matrices, Chiral pharmaceuticals, Chiral stationary phases, Enantioselective chromatography, Environmental matrices",
author = "Ribeiro, {Ana R.} and Maia, {Alexandra S.} and Cass, {Quezia B.} and Tiritan, {Maria E.}",
note = "Funding Information: This work has been supported by Funda{\c c}{\~a}o para a Ci{\^e}ncia e Tecnologia–FCT (PhD grants attributed to Ana Rita Ribeiro, SFRH/BD/64999/2009 and Alexandra Sofia Maia, SFRH/BD/86939/2012, QREN-POPH, European Social Fund and MCTES. This work was also supported by FCT Projects FLUOROPHARMA PTDC/EBB-EBI/111699/2009, PEst-OE/EQB/LA0016/2011 and CEQUIMED PEst-OE/SAU/UI4040/2011. This work was funded also by grant from National Council for Scientific and Technological Development (CNPq). Publisher Copyright: {\textcopyright} 2014 Elsevier B.V.. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",
year = "2014",
month = sep,
day = "15",
doi = "10.1016/j.jchromb.2014.02.049",
language = "English",
volume = "968",
pages = "8--21",
journal = "Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences",
issn = "1570-0232",
publisher = "Elsevier B.V.",
}