Abstract
Gardnerella vaginalis is the most frequent microorganism found in bacterial vaginosis (BV), while Escherichia coli and Enterococcus faecalis are amongst the most frequent pathogens found in urinary tract infections (UTIs). This study aimed to evaluate possible interactions between UTIs pathogens and G. vaginalis using an in vitro dual-species biofilm model. Our results showed that dual-species biofilms reached significantly higher bacterial concentration than monospecies biofilms. Moreover, visualization of dual-populations species in the biofilms, using the epifluorescence microscopy, revealed that all of the urogenital pathogens coexisted with G. vaginalis. In conclusion, our work demonstrates that uropathogens can incorporate into mature BV biofilms.
| Original language | English |
|---|---|
| Journal | Pathogens and Disease |
| Volume | 74 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1 Apr 2016 |
| Externally published | Yes |
Keywords
- Bacterial vaginosis
- Mixed biofilms
- Urinary tract infection
- Uropathogens