Ethylene oxide (EO) sterilization of healthcare products

G. C. Mendes, T. R. S. Brandão, C. L. M. Silva*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

9 Citations (Scopus)


Ethylene oxide is a dominant agent in the sterilization of medical devices due to its effectiveness and compatibility with most materials. The advantages and disadvantages, as well as its recommended uses, are explored in this chapter. The variables and their relevance on process optimization are described, the types of processing cycles are detailed and emphasis is given to the design and validation of the sterilization process.
Original languageEnglish
Title of host publicationSterilisation of biomaterials and medical devices
PublisherElsevier Ltd.
Number of pages26
ISBN (Print)9781845699321
Publication statusPublished - 1 Sep 2012


  • Ethylene oxide sterilization
  • Medical devices
  • Process design
  • Process validation


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