Abstract
Background & Aims: Fecal microbiota transplantation (FMT) is effective for recurrent Clostridium difficile infection (CDI). Intestinal decolonization of carbapenamase-producing-enterobacteriaceae (CPE) can prevent transmission and infection by these agents. The aim of this study was to assess CPE decolonization after FMT. Methods: Case-series study that consecutively included all CPE-carriers that underwent FMT between 2014-2019. The indications included refractory/recurrent CDI and CPE-decolonization. Results: Out of 21 CPE-carriers, 8 were excluded due to incomplete post-FMT testing. CPE decolonization was confirmed in 76.9% (n=10). The median decolonization time was 16-weeks (IQR-23) and ranged from 2-53 weeks. Conclusion: FMT may be used in the clinical practice for CPE-decolonization as an alternative to combined antibiotic regimens.
Original language | English |
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Pages (from-to) | 925-928 |
Number of pages | 4 |
Journal | Revista Espanola de Enfermedades Digestivas |
Volume | 112 |
Issue number | 12 |
DOIs | |
Publication status | Published - Oct 2020 |
Keywords
- Carbapenamase-producing enterobacteriaceae
- Decolonization
- Fecal microbiota transplantation
- Intestinal carriage
- Multidrug-resistant infections