Identification of H-type BSE in Portugal

Leonor Orge, Carla Guedes Machado, Luísa Ramalho, Renata Carvalho, João Silva, Paula Almeida, Paula Tavares, Cristina Ochoa, Carla Lima, Maria J.Marques Pinto, J. Pedro Simas*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

During the bovine spongiform encephalopathy (BSE) epidemic, Portugal was the third most affected country. As a result of a successful national eradication plan, the number of BSE affected animals has been progressively declining in Portugal with no cases identified in 2013. However, within the scope of this active surveillance scheme, we have identified the first H-type BSE case born after the introduction of the reinforced ban in fallen stock. Here, we report the phenotypic features of this case and the analysis of the protein coding sequence of prnp as well as the prnp promoter and intron 1 insertion-deletions.
Original languageEnglish
Pages (from-to)22-28
Number of pages7
JournalPrion
Volume9
Issue number1
DOIs
Publication statusPublished - 10 Feb 2015
Externally publishedYes

Keywords

  • H-BSE
  • Portugal
  • Prnp
  • PrPres

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