Impact of polyphenols on human gut microbiome and associated biomarkers

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Citations (Scopus)


Phenolic compounds have long been recognized for their potential health modulatory effects. From a straightforward antioxidant capacity to metabolic modulation, the literature on their health-related effects evidence their potential. A similar affirmation may be made for the gut microbiome, where positive modulation has been associated with the reduction of risk/amelioration of some pathologies. Most of the ingested phenolic compounds reach the colon; therefore it stands to reason that they may have a modulatory impact upon the gut microbiome. In fact, they have been reported as being capable of stimulating the growth of potentially beneficial species and inhibiting potentially harmful ones, thus exerting a dual effect upon the gut microbiome. Moreover, the microbiota also influences the phenolic composition by mediating reactions that result in new compounds (with different biological activities).

Original languageEnglish
Title of host publicationTechnologies to recover polyphenols from agrofood by-products and wastes
EditorsManuela Estevez Pintado, Jorge Manuel Alexandre Saraiva, Elisabete Maria da Cruz Alexandre
Number of pages16
ISBN (Electronic)9780323852739
ISBN (Print)9780323852746
Publication statusPublished - 1 Jan 2022


  • (Poly)phenols
  • Duplibiotic
  • Gut microbiota
  • Metabolites
  • Nutrition
  • Prebiotic


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