TY - JOUR
T1 - Innovative properties of sustainable galactomannans from seeds of Adenanthera pavonina, Caesalpinia pulcherrima and Delonix regia
AU - Costa, Marcilia P.
AU - Geronço, Maurycyo S.
AU - Ramos, Igor F. da S.
AU - Lucena, Monalisa de A.
AU - Araújo, Ricardo
AU - Pinheiro, Iluska M.
AU - Sousa, Rayran Walter R. de
AU - Ferreira, Paulo Michel P.
AU - Osajima, Josy A.
AU - Amorin, Manuela
AU - Ramos, Óscar
AU - Silva-Filho, Edson C.
AU - Ribeiro, Alessandra B.
AU - Rizzo, Marcia dos S.
N1 - Publisher Copyright:
© 2025 Elsevier Ltd
PY - 2025/7/1
Y1 - 2025/7/1
N2 - Given the importance of new renewable resources for the industrial sector, this study aimed to assess the innovative technological and biological properties of galactomannans derived from the seeds of Adenanthera pavonina (BioAp), Caesalpinia pulcherrima (BioCp), and Delonix regia (BioDr). The biopolymers were evaluated using various parameters, including texture, spreadability, cytocompatibility, hemocompatibility, antimicrobial assays, mucoadhesiveness, and irritation potential by HET-CAM test. The absence of cytotoxicity, hemolysis, and irritation showed the potential of the three biopolymers for applications in biomedical fields. BioAp and BioDr samples exhibited the most effective antimicrobial activity, with MICs of 512 μg mL−1 against Staphylococcus aureus, Escherichia coli, and Candida albicans strains. The BioDr sample would be ideal for developing mucoadhesives due to its superior mucoadhesiveness in both powder and colloidal dispersion forms, achieving the highest Fmax adhesion force values of 0.46 N and 0.08 N, respectively. These findings expand the range of applications for these biopolymers and highlight their potential for integration into innovative polymer products in the food, cosmetics, and pharmaceutical sectors.
AB - Given the importance of new renewable resources for the industrial sector, this study aimed to assess the innovative technological and biological properties of galactomannans derived from the seeds of Adenanthera pavonina (BioAp), Caesalpinia pulcherrima (BioCp), and Delonix regia (BioDr). The biopolymers were evaluated using various parameters, including texture, spreadability, cytocompatibility, hemocompatibility, antimicrobial assays, mucoadhesiveness, and irritation potential by HET-CAM test. The absence of cytotoxicity, hemolysis, and irritation showed the potential of the three biopolymers for applications in biomedical fields. BioAp and BioDr samples exhibited the most effective antimicrobial activity, with MICs of 512 μg mL−1 against Staphylococcus aureus, Escherichia coli, and Candida albicans strains. The BioDr sample would be ideal for developing mucoadhesives due to its superior mucoadhesiveness in both powder and colloidal dispersion forms, achieving the highest Fmax adhesion force values of 0.46 N and 0.08 N, respectively. These findings expand the range of applications for these biopolymers and highlight their potential for integration into innovative polymer products in the food, cosmetics, and pharmaceutical sectors.
KW - Antimicrobial activity
KW - Biopolymer
KW - Cytocompatibility
KW - Mucoadhesion
UR - http://www.scopus.com/inward/record.url?scp=105002320145&partnerID=8YFLogxK
U2 - 10.1016/j.carbpol.2025.123580
DO - 10.1016/j.carbpol.2025.123580
M3 - Article
C2 - 40306786
AN - SCOPUS:105002320145
SN - 0144-8617
VL - 359
JO - Carbohydrate Polymers
JF - Carbohydrate Polymers
M1 - 123580
ER -
