M.O.I.S.T. concept for the local therapy of chronic wounds: an international update

Joachim Dissemond*, Paul Chadwick, Dot Weir, Paulo Alves, Kirsi Isoherranen, José Luis Lázaro Martínez, Terry Swanson, Andrea Gledhill, Matthew Malone

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review



Chronic wounds remain a significant clinical challenge both for those affected and for healthcare systems. The treatment is often comprised and complex. All patients should receive wound care that is integrated into a holistic approach involving local management that addresses the underlying etiology and provides for gold standard therapy to support healing, avoid complications and be more cost effective. There have been significant advances in medicine over the last few decades. The development of new technologies and therapeutics for the local treatment of wounds is also constantly increasing. To help standardize clinical practice with regard to the multitude of wound products, the M.O.I.S.T. concept was developed by a multidisciplinary expert group. The M stands for moisture balance, O for oxygen balance, I for infection control, S for supporting strategies, and T for tissue management. Since the M.O.I.S.T. concept, which originated in the German-speaking countries, is now intended to provide healthcare professionals with an adapted instrument to be used in clinical practice, and a recent update to the concept has been undertaken by a group of interdisciplinary experts to align it with international standards. The M.O.I.S.T. concept can now be used internationally both as an educational tool and for the practical implementation of modern local treatment concepts for patients with chronic wounds and can also be used in routine clinical practice.

Original languageEnglish
Number of pages9
JournalInternational Journal of Lower Extremity Wounds
Publication statusAccepted/In press - 2024


  • Chronic wounds
  • Local therapy
  • M.O.I.S.T. concept
  • Wound healing
  • Wound treatment


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