TY - JOUR
T1 - NRS-2002 for pre-treatment nutritional risk screening and nutritional status assessment in head and neck cancer patients
AU - Orell-Kotikangas, Helena
AU - Österlund, Pia
AU - Saarilahti, Kauko
AU - Ravasco, Paula
AU - Schwab, Ursula
AU - Mäkitie, Antti A.
N1 - Funding Information:
This study was financially supported by grants from the Finnish Cultural Foundation and the Helsinki University Central Hospital Research Funds, Helsinki, Finland. The study sponsors did not have any involvement in the study design, data collection, analysis and interpretation of data, the writing of the manuscript and in the decision to submit the manuscript for publication.
Publisher Copyright:
© 2014, Springer-Verlag Berlin Heidelberg.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Background: The aim of this study was to assess the value of nutritional risk screening-2002 (NRS-2002) as a nutritional risk screening and status assessment method and to compare it with nutritional status assessed by subjective and objective methods in the screening of head and neck cancer patients. Methods: Sixty-five consecutive patients (50 male), with a median age of 61 years (range, 33–77), with head and neck squamous cell carcinoma (HNSCC) were enrolled prior to cancer therapy. Nutritional status was assessed by NRS-2002, patient-generated subjective global assessment (PG-SGA), handgrip strength (HGS) and mid-arm muscle area (MAMA). Results: Twenty-eight percent of patients were at nutritional risk based on NRS-2002, and 34 % were malnourished according to PG-SGA, while 43 % had low HGS. NRS-2002 cut-off score of ≥3 compared with the nutritional status according to PG-SGA showed 77 % specificity and 98 % sensitivity (K = 0.78). NRS-2002 was able to predict malnutrition (PG-SGA BC) both in men (p < 0.001) and in women (p < 0.05). NRS-2002 identified correctly patients with malnutrition with a score of ≥3 (p < 0.001) and risk patients with a score of ≥2 (p < 0.001). Conclusions: These results suggest that NRS-2002 seems to be a reliable indicator of malnutrition, while NRS-2002 with the cut-off score of ≥2 seems to be more reliable for nutrition screening in head and neck cancer patients prior to oncological treatment.
AB - Background: The aim of this study was to assess the value of nutritional risk screening-2002 (NRS-2002) as a nutritional risk screening and status assessment method and to compare it with nutritional status assessed by subjective and objective methods in the screening of head and neck cancer patients. Methods: Sixty-five consecutive patients (50 male), with a median age of 61 years (range, 33–77), with head and neck squamous cell carcinoma (HNSCC) were enrolled prior to cancer therapy. Nutritional status was assessed by NRS-2002, patient-generated subjective global assessment (PG-SGA), handgrip strength (HGS) and mid-arm muscle area (MAMA). Results: Twenty-eight percent of patients were at nutritional risk based on NRS-2002, and 34 % were malnourished according to PG-SGA, while 43 % had low HGS. NRS-2002 cut-off score of ≥3 compared with the nutritional status according to PG-SGA showed 77 % specificity and 98 % sensitivity (K = 0.78). NRS-2002 was able to predict malnutrition (PG-SGA BC) both in men (p < 0.001) and in women (p < 0.05). NRS-2002 identified correctly patients with malnutrition with a score of ≥3 (p < 0.001) and risk patients with a score of ≥2 (p < 0.001). Conclusions: These results suggest that NRS-2002 seems to be a reliable indicator of malnutrition, while NRS-2002 with the cut-off score of ≥2 seems to be more reliable for nutrition screening in head and neck cancer patients prior to oncological treatment.
KW - Nutritional risk screening
KW - Nutritional status
KW - Patient-generated subjective global assessment
UR - http://www.scopus.com/inward/record.url?scp=84937406277&partnerID=8YFLogxK
U2 - 10.1007/s00520-014-2500-0
DO - 10.1007/s00520-014-2500-0
M3 - Article
C2 - 25370893
AN - SCOPUS:84937406277
SN - 0941-4355
VL - 23
SP - 1495
EP - 1502
JO - Supportive Care in Cancer
JF - Supportive Care in Cancer
IS - 6
ER -