Optical fiber biosensor based on enzymatic coating matrix for catecholamines assessment in human urine

Lurdes I.B. Silva, Ana C. Freitas, Teresa A. P. Rocha-Santos, M. E. Pereira, Armando C. Duarte

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

An optical fiber (OF) biosensor has been developed and applied for simultaneous determination of catecholamines (dopamine, norepinephrine and epinephrine) in human urine. The developed analytical device shows a high potential for catecholamines quantification with a detection limit of 2.1, 2.6 and 3.4 pg mL-1 for dopamine, norepinephrine and epinephrine, respectively. The analytical performance of the OF biosensor was found to be similar to that of the High Performance Liquid Chromatography - Electrochemical Detector (HPLC-ED) regarding catecholamines determination in samples of human urine.

Original languageEnglish
Title of host publicationFourth European Workshop on Optical Fibre Sensors
DOIs
Publication statusPublished - 2010
Externally publishedYes
Event4th European Workshop on Optical Fibre Sensors - Porto, Portugal
Duration: 8 Sept 201010 Sept 2010

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7653
ISSN (Print)0277-786X

Conference

Conference4th European Workshop on Optical Fibre Sensors
Country/TerritoryPortugal
CityPorto
Period8/09/1010/09/10

Keywords

  • Biosensor
  • Catecholamines measurement
  • Optical fiber sensor
  • Urine analysis

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