TY - JOUR
T1 - Oral and gastric helicobacter pylori
T2 - effects and associations
AU - Veiga, Nélio
AU - Pereira, Carlos
AU - Resende, Carlos
AU - Amaral, Odete
AU - Ferreira, Manuela
AU - Nelas, Paula
AU - Chaves, Claudia
AU - Duarte, João
AU - Cirnes, Luis
AU - Machado, José Carlos
AU - Ferreira, Paula
AU - Correia, Ilídio J.
PY - 2015/5/1
Y1 - 2015/5/1
N2 - Introduction This study consisted in the comparison of the prevalence of Helicobacter pylori (H. pylori) present in the stomach and in saliva of a sample of Portuguese adolescents and the assessment of the association between H. pylori infection with socio-demographic variables and prevalence of dental caries. Materials and Methods A cross-sectional study was designed including a sample of 447 adolescents aged 12 to 19 years old, attending a public school in Sátão, Portugal. A questionnaire about socio-demographic variables and oral health behaviors was applied. Gastric H. pylori infection was determined using the urease breath test (UBT). Saliva collection was obtained and DNA was extracted by Polymerase Chain Reaction (PCR) in order to detect the presence of oral H. pylori. Results The prevalence of gastric H. pylori detected by UBT was 35.9%. Within the adolescents with a gastric UBT positive, only 1.9% were positive for oral H. pylori. The presence of gastric H. pylori was found to be associated with age (>15years, Odds ratio(OR)=1.64,95% CI=1.08-2.52), residence area (urban,OR=1.48,95%CI=1.03-2.29) and parents' professional situation (unemployed,OR=1.22,95%CI=1.02-1.23). Among those with detected dental caries during the intra-oral observation, 37.4% were positive for gastric H. pylori and 40.2% negative for the same bacterial strain (p=0.3). Conclusions The oral cavity cannot be considered a reservoir for infection of H. pylori. Gastric H. pylori infection was found to be associated with socio-demographic variables such as age, residence area and socioeconomic status.
AB - Introduction This study consisted in the comparison of the prevalence of Helicobacter pylori (H. pylori) present in the stomach and in saliva of a sample of Portuguese adolescents and the assessment of the association between H. pylori infection with socio-demographic variables and prevalence of dental caries. Materials and Methods A cross-sectional study was designed including a sample of 447 adolescents aged 12 to 19 years old, attending a public school in Sátão, Portugal. A questionnaire about socio-demographic variables and oral health behaviors was applied. Gastric H. pylori infection was determined using the urease breath test (UBT). Saliva collection was obtained and DNA was extracted by Polymerase Chain Reaction (PCR) in order to detect the presence of oral H. pylori. Results The prevalence of gastric H. pylori detected by UBT was 35.9%. Within the adolescents with a gastric UBT positive, only 1.9% were positive for oral H. pylori. The presence of gastric H. pylori was found to be associated with age (>15years, Odds ratio(OR)=1.64,95% CI=1.08-2.52), residence area (urban,OR=1.48,95%CI=1.03-2.29) and parents' professional situation (unemployed,OR=1.22,95%CI=1.02-1.23). Among those with detected dental caries during the intra-oral observation, 37.4% were positive for gastric H. pylori and 40.2% negative for the same bacterial strain (p=0.3). Conclusions The oral cavity cannot be considered a reservoir for infection of H. pylori. Gastric H. pylori infection was found to be associated with socio-demographic variables such as age, residence area and socioeconomic status.
UR - http://www.scopus.com/inward/record.url?scp=84959278408&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0126923
DO - 10.1371/journal.pone.0126923
M3 - Article
C2 - 26010595
AN - SCOPUS:84959278408
SN - 1932-6203
VL - 10
JO - PLoS one
JF - PLoS one
IS - 5
M1 - e0126923
ER -
