Pharmaceutical and biomedical potential of sulphated polysaccharides from algae

Alcina M. M. B. Morais, A. J. Alves, D. Kumla, Rui M. S. C. Morais*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

In recent years, sulphated polysaccharides (SPs) have emerged as an increasingly important class of biopolymers with potential innovative applications in the biomedical and pharmaceutical fields due to their diverse physicochemical properties and biological activities. The focus of the present chapter is to describe these biological activities and pharmacological properties of SPs and to highlight their potential application in the pharmaceutical and biomedical areas, as well. These compounds obtained from algae (macroalgae and microalgae) exhibit many beneficial biological activities, such as anticoagulant and/or antithrombotic, immunomodulator, antitumor and cancer preventive, hypoglycemic, antibiotics and anti-inflammatory, and antioxidant. In addition, the interest in using algal polysaccharides as biomedical vehicles for drug delivery has increased steadily. The isolation, structure elucidation, and bioactivity testing of algal SPs always bring perspectives for the discovery of new drugs and new applications, as well as an economic development, both by introducing a high diversity of new products and, eventually, a product with high added value.

Original languageEnglish
Title of host publicationPolysaccharides of microbial origin
EditorsJoaquim Oliveira, Hajer Radhouani, Rui L. Reis
PublisherSpringer Nature Switzerland AG
Pages893-920
Number of pages28
ISBN (Electronic)9783030422165
ISBN (Print)9783030422141
DOIs
Publication statusPublished - 1 Jan 2022

Keywords

  • Biological activities
  • Biomedical applications
  • Macroalge
  • Microalgae
  • Sulphated polysaccharides

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