TY - JOUR
T1 - Polyelectrolyte precipitation
T2 - a new green chemistry approach to recover value-added proteins from different sources in a circular economy context
AU - Gómez-García, Ricardo
AU - Vilas-Boas, Ana A.
AU - Vilas-Boas, Ana Martins
AU - Campos, Débora A.
AU - Pintado, Manuela
N1 - Funding Information:
All the authors would like to thank the scientific collaboration of Escola Superior de Biotecnologia of Universidade Católica Portuguesa through CBQF as well as to the FCT—Fundação para a Ciência e a Tecnologia for the funding research grants given to Ana A. Vilas-Boas and Débora A. Campos.
Funding Information:
The author Ana A. Vilas-Boas would like to acknowledge the Fundação para a Ciência e a Tecnologia—Portugal (FCT) for the individual Ph.D. grant (2020.05655.BD). Also, Débora A. Campos acknowledges the FCT for the given support through the Individual Junior Research contract (2021.01947.CEECIND).
Publisher Copyright:
© 2022 by the authors.
PY - 2022/8/11
Y1 - 2022/8/11
N2 - Proteins have always been vital biological molecules used for industrial purposes, human nutrition and health. Nowadays, seeking new alternatives and sources of these biomolecules is becoming an increasing research trend derived from the present consumer awareness between food consumption and health promotion, but also on environmental sustainability. Although there are different consolidated/traditional downstream processes to obtain proteins, such as chromatography tools, alkali hydrolysis, precipitation by inorganic salts and organic solvents, their industrial-scale application still demands urgent innovation due to the poor recovery yields, high costs and time-consuming steps, environmental impact as well as some toxic concerns. Polyelectrolyte precipitation represents a green, innovative alternative for protein recovery; however, there are reduced data regarding its pilot or industrial-scale application. In this literature work, the action mechanism and principles with regards to its functionality and insights for its application on a big scale are reviewed. Overall, this review discusses the novelty and sustainability of protein precipitation by polyelectrolytes from different sources against traditional techniques as well as highlights the relationship between protein source, production relevance and bioactive properties that are key factors to maximize the application of this extractive method on a circular economy context.
AB - Proteins have always been vital biological molecules used for industrial purposes, human nutrition and health. Nowadays, seeking new alternatives and sources of these biomolecules is becoming an increasing research trend derived from the present consumer awareness between food consumption and health promotion, but also on environmental sustainability. Although there are different consolidated/traditional downstream processes to obtain proteins, such as chromatography tools, alkali hydrolysis, precipitation by inorganic salts and organic solvents, their industrial-scale application still demands urgent innovation due to the poor recovery yields, high costs and time-consuming steps, environmental impact as well as some toxic concerns. Polyelectrolyte precipitation represents a green, innovative alternative for protein recovery; however, there are reduced data regarding its pilot or industrial-scale application. In this literature work, the action mechanism and principles with regards to its functionality and insights for its application on a big scale are reviewed. Overall, this review discusses the novelty and sustainability of protein precipitation by polyelectrolytes from different sources against traditional techniques as well as highlights the relationship between protein source, production relevance and bioactive properties that are key factors to maximize the application of this extractive method on a circular economy context.
KW - Circular economy
KW - Food waste
KW - Green process
KW - Ionic precipitation
KW - Plant-based proteins
KW - Polyelectrolytes
KW - Protein recovery
KW - Sustainability
UR - http://www.scopus.com/inward/record.url?scp=85136536770&partnerID=8YFLogxK
U2 - 10.3390/molecules27165115
DO - 10.3390/molecules27165115
M3 - Review article
C2 - 36014354
AN - SCOPUS:85136536770
SN - 1420-3049
VL - 27
JO - Molecules (Basel, Switzerland)
JF - Molecules (Basel, Switzerland)
IS - 16
M1 - 5115
ER -
