TY - JOUR
T1 - Prebiotic effect, bioactive compounds and antioxidant capacity of melon peel (Cucumis melo L. inodorus) flour subjected to in vitro gastrointestinal digestion and human faecal fermentation
AU - Gómez-García, Ricardo
AU - Sánchez-Gutiérrez, Mónica
AU - Freitas-Costa, Célia
AU - Vilas-Boas, Ana A.
AU - Campos, Débora A.
AU - Aguilar, Cristóbal N.
AU - Madureira, Ana R.
AU - Pintado, Manuela
N1 - Funding Information:
The authors would like to thank the National Council of Science and Technology (CONACyT, Mexico) for PhD fellowship support granted to Gómez-García Ricardo and also the authors would like to thank to the project MultiBiorefinery .: Estratégias multiuso para a valorização de uma gama alargada de subprodutos agroflorestais e das pescas: Um passo em frente na criação de uma biorrefinaria“ financiado pelo Programa Operacional Competitividade e Internacionalização (POCI-01-0145-FEDER-016403) e pelo Programa Operacional Regional de Lisboa (LISBOA-01-0145-FEDER-016403), na sua componente FEDER e pela Fundação para a Ciência e Tecnologia, I.P. na componente nacional (SAICTPAC/0040/2015).
Funding Information:
The authors would like to thank the National Council of Science and Technology (CONACyT, Mexico) for PhD fellowship support granted to G?mez-Garc?a Ricardo and also the authors would like to thank to the project MultiBiorefinery.: Estrat?gias multiuso para a valoriza??o de uma gama alargada de subprodutos agroflorestais e das pescas: Um passo em frente na cria??o de uma biorrefinaria? financiado pelo Programa Operacional Competitividade e Internacionaliza??o (POCI-01-0145-FEDER-016403) e pelo Programa Operacional Regional de Lisboa (LISBOA-01-0145-FEDER-016403), na sua componente FEDER e pela Funda??o para a Ci?ncia e Tecnologia, I.P. na componente nacional (SAICTPAC/0040/2015).
Publisher Copyright:
© 2022
PY - 2022/4
Y1 - 2022/4
N2 - Melon peels are by-products derived from food processing industries, representing potential sources of new ingredients in particular dietary fibre and phenolic compounds, which in synergy could exert beneficial effects on human health. The objective of this study was to evaluate the accessibility of bioactive compounds from melon peels throughout gastrointestinal digestion and evaluate their prebiotic effect when submitted to in vitro human faecal fermentation. Melon peels flour obtained from solid fraction showed an increase in antioxidant capacity at the gastric and intestinal phase, which was corroborated by the total phenolic content (126.91%) increase and the identified individual phenolics (tyrosol, luteolin-6-glycoside, chlorogenic and caffeic acids). Also, melon peels flour positively impacted the gut microbiota diversity, showing a similar ratio of Firmicutes/Bacteroidetes compared to the positive control (FOS) and promoted the production of short-chain fatty acids, mainly acetate > propionate > butyrate. Thus, these findings demonstrate that melon peels have antioxidant and prebiotic potential attributed to the phenolic compounds and the production of beneficial fatty acids, which could improve human gut health.
AB - Melon peels are by-products derived from food processing industries, representing potential sources of new ingredients in particular dietary fibre and phenolic compounds, which in synergy could exert beneficial effects on human health. The objective of this study was to evaluate the accessibility of bioactive compounds from melon peels throughout gastrointestinal digestion and evaluate their prebiotic effect when submitted to in vitro human faecal fermentation. Melon peels flour obtained from solid fraction showed an increase in antioxidant capacity at the gastric and intestinal phase, which was corroborated by the total phenolic content (126.91%) increase and the identified individual phenolics (tyrosol, luteolin-6-glycoside, chlorogenic and caffeic acids). Also, melon peels flour positively impacted the gut microbiota diversity, showing a similar ratio of Firmicutes/Bacteroidetes compared to the positive control (FOS) and promoted the production of short-chain fatty acids, mainly acetate > propionate > butyrate. Thus, these findings demonstrate that melon peels have antioxidant and prebiotic potential attributed to the phenolic compounds and the production of beneficial fatty acids, which could improve human gut health.
KW - Antioxidants
KW - Dietary fibre
KW - Functional ingredients
KW - Gut health
KW - Phenolic compounds
KW - Simulated digestion
UR - http://www.scopus.com/inward/record.url?scp=85125235935&partnerID=8YFLogxK
U2 - 10.1016/j.foodres.2022.111045
DO - 10.1016/j.foodres.2022.111045
M3 - Article
C2 - 35337586
AN - SCOPUS:85125235935
SN - 0963-9969
VL - 154
JO - Food research international
JF - Food research international
M1 - 111045
ER -