Prevalence of viral hepatitis B and C in riverside communities of the Tucuruí Dam, Pará, Brazil

Marcella Kelly Costa de Almeida, Kemper Nunes dos Santos, Amanda Alves Fecury, Cláudia Suellen Ferro de Oliveira, Andrei Silva Freitas, Juarez Antonio Simões Quaresma, Hellen Thais Fuzii, Luisa Caricio Martins*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Epidemiologically, the relevance of infection caused by hepatitis viruses is related mainly to their wide geographic distribution and the large number of infected individuals in all parts of the world. In this study, 668 residents from the islands around the Tucuruí Dam were selected. Blood samples were collected for investigation of serological markers (HBsAg, total anti-HBc, anti-HBS, and anti-HCV) by enzyme immunoassays. HCV-positive subjects were tested using RT-PCR and RFLP for the identification of viral genotypes. Among the 668 subjects studied, 1.9% were HBsAg positive, 28% were total anti-HBc positive, and 41.9% were anti-HBs positive. The anti-HBs marker alone (vaccine response) was detected in 25.7% of the volunteers. Anti-HCV antibody was detected in 2.2% of the subjects and genotype 1 was the predominant genotype (70%). The results indicate an intermediate level of HBV and HCV endemicity in the region studied, as well as low HBV vaccination coverage.

Original languageEnglish
Pages (from-to)1907-1912
Number of pages6
JournalJournal of Medical Virology
Volume84
Issue number12
DOIs
Publication statusPublished - Dec 2012
Externally publishedYes

Keywords

  • HBV
  • HCV
  • Molecular biology
  • Riverside communities

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