Salt-cured atlantic cod skin: a sustainable source of acid-soluble type I collagen

Ezequiel R. Coscueta*, María Emilia Brassesco, Manuela Pintado*

*Corresponding author for this work

Research output: Working paperPreprint



Collagen is the most abundant protein in the animal kingdom. Industrial collagen is mainly bovine and porcine origin. However, due to religious beliefs, allergic issues, and infectious diseases, alternative sources of collagen as marine are gaining increasing interest. In this work, the acid-soluble collagen (ASC) were extracted from salt-cured Atlantic cod (Gadus morhua) skin and characterized. The extraction yield was about 2.0%, equivalent to the extraction yield reported for other fish skins. The electrophoretic pattern showed the typical type I structure (α, β and γ chains). UV-VIS and FTIR absorbance spectra suggested a very pure ASC with an intact triple helical structure. The integrity and the adequate porosity required for different applications were then confirmed by electron micrograph. Our findings allow us to say that, for the first time, we extracted acid-soluble type I collagen from salt-cured Atlantic cod skin, with characteristics suitable for application in various fields, such as biomedical.
Original languageEnglish
Number of pages9
Publication statusPublished - 17 Feb 2021


  • Salt-cured cod skin
  • Gadus morhua
  • Collagen
  • Fishery by-products
  • Biomaterials


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