Stability study of squalane and hemisqualane derived from synthetic biology

Francisca S Teixeira; Lígia L. Pimentel; Susana S. M. P. Vidigal; Paula T. Costa; Manuela E. Pintado; Luís M. Rodríguez-Alcalá

Stability study of squalane and hemisqualane derived from synthetic biology

Francisca S Teixeira, Lígia L. Pimentel^*, Susana S. M. P. Vidigal, Paula T. Costa, Manuela E. Pintado, Luís M. Rodríguez-Alcalá

^*Corresponding author for this work

Research output: Contribution to conference › Poster

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Abstract

Lipids obtained through fermentative processes have emerged as an excellent alternative to produce high-value molecules without compromising natural resources and meeting sustainable requirements [1]. A good example is squalene, the precursor of cholesterol in humans, known by protecting skin against UV radiation. It has been recently shown to reduce side-effects of chemotherapy and is widely used as adjuvant for pharmaceutical applications [2,3]. However, squalene is an unsaturated lipid and therefore susceptible to undergo oxidation. As a more stable alternative, processes to produce commercial squalane (SQ) and hemisqualane (HSQ) have been also developed.

Original language	English
Number of pages	1
Publication status	Published - 2021
Event	18th Euro Fed Lipid Congress and Expo - Online, Germany Duration: 18 Oct 2021 → 21 Oct 2021

Conference

Conference	18th Euro Fed Lipid Congress and Expo
Country/Territory	Germany
Period	18/10/21 → 21/10/21

Access to Document

41052627Final published version, 1.17 MBLicence: Unspecified

http://hdl.handle.net/10400.14/37593Licence: Unspecified

ALCHEMY: Capturing High Value from Industrial Fermentation BioProducts
Pintado, M. M. (PI) & Pimentel, L. (Researcher)
1/01/18 → 30/06/23
Project: Research

Cite this

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title = "Stability study of squalane and hemisqualane derived from synthetic biology",

abstract = "Lipids obtained through fermentative processes have emerged as an excellent alternative to produce high-value molecules without compromising natural resources and meeting sustainable requirements [1]. A good example is squalene, the precursor of cholesterol in humans, known by protecting skin against UV radiation. It has been recently shown to reduce side-effects of chemotherapy and is widely used as adjuvant for pharmaceutical applications [2,3]. However, squalene is an unsaturated lipid and therefore susceptible to undergo oxidation. As a more stable alternative, processes to produce commercial squalane (SQ) and hemisqualane (HSQ) have been also developed.",

author = "Teixeira, {Francisca S} and Pimentel, {L{\'i}gia L.} and Vidigal, {Susana S. M. P.} and Costa, {Paula T.} and Pintado, {Manuela E.} and Rodr{\'i}guez-Alcal{\'a}, {Lu{\'i}s M.}",

year = "2021",

language = "English",

note = "18th Euro Fed Lipid Congress and Expo ; Conference date: 18-10-2021 Through 21-10-2021",

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TY - CONF

T1 - Stability study of squalane and hemisqualane derived from synthetic biology

AU - Teixeira, Francisca S

AU - Pimentel, Lígia L.

AU - Vidigal, Susana S. M. P.

AU - Costa, Paula T.

AU - Pintado, Manuela E.

AU - Rodríguez-Alcalá, Luís M.

PY - 2021

Y1 - 2021

N2 - Lipids obtained through fermentative processes have emerged as an excellent alternative to produce high-value molecules without compromising natural resources and meeting sustainable requirements [1]. A good example is squalene, the precursor of cholesterol in humans, known by protecting skin against UV radiation. It has been recently shown to reduce side-effects of chemotherapy and is widely used as adjuvant for pharmaceutical applications [2,3]. However, squalene is an unsaturated lipid and therefore susceptible to undergo oxidation. As a more stable alternative, processes to produce commercial squalane (SQ) and hemisqualane (HSQ) have been also developed.

AB - Lipids obtained through fermentative processes have emerged as an excellent alternative to produce high-value molecules without compromising natural resources and meeting sustainable requirements [1]. A good example is squalene, the precursor of cholesterol in humans, known by protecting skin against UV radiation. It has been recently shown to reduce side-effects of chemotherapy and is widely used as adjuvant for pharmaceutical applications [2,3]. However, squalene is an unsaturated lipid and therefore susceptible to undergo oxidation. As a more stable alternative, processes to produce commercial squalane (SQ) and hemisqualane (HSQ) have been also developed.

M3 - Poster

T2 - 18th Euro Fed Lipid Congress and Expo

Y2 - 18 October 2021 through 21 October 2021

ER -

Stability study of squalane and hemisqualane derived from synthetic biology

Abstract

Conference

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Projects

ALCHEMY: Capturing High Value from Industrial Fermentation BioProducts

Cite this