The insect reservoir of biodiversity for viruses and for antiviral mechanisms

Roenick Proveti Olmo*, Nelson Eduardo Martins, Eric Roberto G.R. Aguiar, João T. Marques, Jean Luc Imler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Insects are the most diverse group of animals. They can be infected by an extraordinary diversity of viruses. Among them, arthropod-borne viruses (arboviruses) can be transmitted to humans. High-throughput sequencing of small RNAs from insects provides insight into their virome, which may help understand the dynamics of vector borne infectious diseases. Furthermore, investigating the mechanisms that restrict viral infections in insects points to genetic innovations that may inspire novel antiviral strategies.

Original languageEnglish
Article numbere20190122
JournalAnais da Academia Brasileira de Ciencias
Volume91
DOIs
Publication statusPublished - 2019
Externally publishedYes

Keywords

  • Antiviral immunity
  • Insects
  • Metagenomics
  • Restriction factors
  • RNA interference
  • Virome

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