The Use of Porphyrins in Photodynamic Therapy of Cutaneous Leishmaniasis

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Leishmaniasis is a disease transmitted by protozoa of the genus Leishmania. Numerous species are responsible
for the infection in humans, resulting in three clinical phenotypes. The therapeutic drug availability for treatment of this
endemic disease is still limited and presents several problems. Photodynamic therapy (PDT) is presented as an alternative
action for the treatment of cutaneous leishmaniasis (CL). Studies suggest that this therapy using porphyrins is relatively
effective in the treatment of CL. However, data are still limited and PDT can not yet be recommended in clinical routine
practice. Moreover, the mechanism of action of this promising therapy still needs to be investigated.
Original languageEnglish
JournalRevista Virtual de Quimica
Publication statusPublished - 2012


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