Theranostics: simultaneous treatment and diagnosis made possible by nanotechnology

João Albuquerque, Ana Rute Neves, Salette Reis*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

There is confusion over the definition of nanotechnology and, partly because of a lack of any standard nomenclature, various inconsistent definitions have sprung up over years. One widely employed definition that is unconstrained by an arbitrary size limitation or dimensionality is listed below: “The design, characterization, production, and application of structures, devices, and systems by controlled manipulation of size and shape at the nanometer scale that produces structures, devices, and systems with at least one novel/superior characteristic or property.” This chapter focuses on the nanotechnology applications for theranostic based approaches in medicine, reviewing what is already being researched in the labs and their possible applications in clinics, as well as other possibilities in the future of medicine and health care. The main goal of theranostics is to develop methodologies that allow treatment and simultaneous follow-up of every patient, with the hope that in the long term the treatment can be tuned for each individual, increasing its efficacy and improving the prognosis.
Original languageEnglish
Title of host publicationAdvances in medical imaging, detection, and diagnosis
EditorsRaj Bawa, Gerald F. Audette, S. R. Bawa, Bela Patel, Bruce D. Johnson, Rajeev Khanna
Place of PublicationNew York
PublisherJenny Stanford Publishing
Pages251-268
Number of pages18
ISBN (Electronic)9781003298038
ISBN (Print)9789814877466
DOIs
Publication statusPublished - 1 Jan 2023
Externally publishedYes

Keywords

  • Apomorphine
  • Arginine-glycine-aspartic acid (RGD)
  • Bioavailability
  • Cancer theranostics
  • Cisplatin
  • Dendrimers
  • Diagnostics
  • DNA transfection
  • Doxorubicin
  • Drug delivery
  • Encapsulation
  • Fluorescein isothiocyanate (FITC)
  • Gene silencing
  • Gold nanoparticles (AuNPs)
  • Graphene
  • Imaging
  • Iron oxide nanoparticles (IONPs)
  • Laser ablation
  • Lipid nanoparticles
  • Liposome
  • Magnetic resonance imaging (MRI)
  • Methotrexate
  • Nanocage
  • Nanocarbons
  • Nanocarriers
  • Nanocrystals
  • Nanomedicine
  • Nanoparticles (NPs)
  • Nanorod
  • Nanosphere
  • Nanostructured lipid carriers (NLCs)
  • Nanotechnology
  • Near-infrared (NIR)
  • Optical properties
  • Paclitaxel
  • Personalized treatment
  • Photodynamic therapy
  • Plasmid DNA
  • Poly(ethylene glycol) (PEG)
  • Polyamidoamine (PAMAM)
  • Polymeric nanoparticles
  • Quantum dots (QDs)
  • Rheumatoid arthritis
  • Small interfering RNA
  • Solid lipid nanoparticles (SLNs)
  • Superparamagnetic
  • Surface functionalization
  • Theranostics
  • Treatment

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