Towards restoring proper chromosome segregation and preventing ageing

Laura Tovini, Sarah E. McClelland*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The natural progressive dysfunction of most living organisms—ageing—has captured the attention of several studies, with the intention to develop rejuvenation strategies. Evidence is emerging of a positive correlation between natural ageing and chromosomal instability (CIN). In this issue of EMBO Reports, Barroso-Vilares et al [1] now show a link between ageing and the erroneous assembly of the apparatus required for a proper cellular division. They compare this mechanism in young and naturally aged human cells and describe a strategy to delay age-related CIN.

Original languageEnglish
Article numbere50322
JournalEMBO Reports
Volume21
Issue number5
DOIs
Publication statusPublished - 6 May 2020
Externally publishedYes

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